American Consequences - July 2021

The CDC study also included paramedics and nursing-home workers – not just hospital staff. However, it included fewer administrators. Virtually everyone in the CDC study had real patient contact. So it was a different trial group in different cities over a different time period than the Cleveland Clinic study. But the outcome was the same. Of the 4,000 health workers the CDC studied, 75% of these folks accepted the vaccine, but it took time to get them all vaccinated. So by the end of the study, there were 78,000 person-days at risk. There were only three infections among these 3,000 people. Meanwhile, among the 1,000 unvaccinated folks, there were 161 infections. However, this reflected more person-days of actual risk – specifically, 116,000 person-days. If you normalize both groups in units of “1,000 days at risk,” unvaccinated health care workers converted to a positive COVID-19 test at a rate of 1.38. For vaccinated folks, the risk per 1,000 days was 0.04. In short, this study again showed that The outcomes in a real-world clinical trial completely validate the Pfizer (PFE) and Moderna (MRNA) trials. These RNA vaccines, collectively, are more than 97% effective in preventing COVID-19 infections.

By day 100, almost two-thirds had their shots, while the other third refused. Overall, the trial lasted 150 days – through May 15, 2021. Since two-thirds of the people were vaccinated by the final one-third of the trial, the “person-days at risk” is roughly equal. The risk in this case is a COVID-19 infection. And “person-days” is how many people are exposed to this risk and for how many days they face the risk. So because the time-and-person balanced risk is close to the same, here’s what we could expect to see if the vaccine did nothing: We would see as many infections in one group as the other. But here’s what we saw: From December 2020 to May 2021, there were 15 COVID-19 infections in the fully vaccinated group. Among the people who refused the vaccine, there were 1,344 infections. The outcomes in a real-world clinical trial completely validate the Pfizer (PFE) and Moderna (MRNA) trials. These RNA vaccines, collectively, are more than 97% effective in preventing COVID-19 infections. We saw 97% prevention of COVID-19 in a second real-world trial, too. This was reported in the U.S. Centers for Disease Control and Prevention’s (“CDC”) “Morbidity and Mortality Weekly Report.” This study came out in early April, so it was only a four-month study from December 2020 to March 2021. Still, it covered eight sites spread across the U.S. It also tracked health care workers.

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