NSLHD News March 11 2022

study to investigate new treatment for acute myeloid leukaemia The Cancer Council NSW

“There are however, high rates of relapse as this form of cancer is protected by a rare group of cells known as leukaemic stem cells, which have the ability to lay dormant and evade chemotherapy. They then reactivate and renew themselves to drive fresh cancer growth. “My team and I recently uncovered a mechanism which is crucial to the survival of leukaemic stem cells. This mechanism is only found in leukaemic stem cells, not in normal human stem cells, making it a promising target for a new treatments.” In this project, Dr Wang and her team will investigate how leukaemic stem cells are able to survive and renew. The team will then develop a treatment strategy to inhibit this unique mechanism “We are very excited by this approach targeting leukaemic stem cells, as this potential new treatment could eradicate acute myeloid in clinically relevant experimental models.

announced funding for a new team at the Kolling Institute to examine a revolutionary approach to treatment for those with acute myeloid leukaemia. This aggressive form of blood cancer has a tragically poor survival rate, and while we have seen tremendous progress for many other types of cancer in recent years, there have been very limited improvements in treatment for this deadly form of blood cancer. Internationally respected researcher Dr Jenny Wang will lead the promising new study following the Cancer Council NSW grant of $450,000. “We are thrilled to have received this generous funding for our project which we hope will lead to an effective, new therapy for this complex cancer,” said the University of Sydney researcher. “Chemotherapy is currently the first-line treatment for acute myeloid leukaemia.

Research Dr Jenny Wang

leukaemia at its root,” she said. “If our pre-clinical tests are successful, we hope to start clinical trials of this innovative approach in collaboration with clinicians and our longstanding industry partner. “This new funding represents an important step towards a greater understanding of this complex cancer and promising new treatment options to improve outcomes for those with this form of blood cancer.” the future of our maternity services. ”We know birthing preferences have changed over time and we aim to meet the needs and expectations of our community, so it’s important we continue to canvass their ideas. “We want to know what’s important to them.” Approximately 10,000 babies are born in NSLHD each year. The survey will be available across the district in places such as maternity wards and child and family health centres

NSLHD undertakes its largest maternity study NSLHD is relaunching a maternity study to survey as many families as possible who have or are planning for a baby to help shape future services. In one of the largest maternity studies undertaken at the households who live in the district. All participants are welcome – even if they chose to give birth in a private facility – or at home. NSLHD’s Acting Network Manager Midwifery Practice

district, we are conducting a month-long survey of families who are planning a pregnancy or have recently given birth. Launched during last year’s COVID-19 outbreak, the survey has undergone a revamp in an effort to boost more responses. The survey will be handed out to patients currently using our maternity services, and will be available online and through social media to reach out to

Jodie Adams said it was important that as many parents filled out the survey so the district could understand the needs of families. “It is important we receive a large number of responses so the district can better understand the needs and preferences of new and expectant families,” she said. “The feedback will help shape

throughout March 2022. It is available by visiting https://bit.ly/3tpiHkD

WWW.NSLHD.HEALTH.NSW.GOV.AU

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