Bile Acid SPLASH ™ Product number 330736
Bile acids have long been known to play important functions in digestion and absorption of lipids. More recently, bile acids have been recognized as important signalling molecules with roles in microbiome homeostasis and metabolic disease. Dysregulation of bile acids can be indicative of various pathologies, making them promising targets of disease research. We created Bile Acid SPLASH so researchers can measure a wide array of bile acids in plasma using one pre-mixed internal standard mixture.
Compound name
Exact mass
Chemical formula
Target conc (µM)
Target conc (µg/mL)
Cholic acid-d4
412.31
C 24 H 36 D 4 O 5
1150
0.474
Taurocholic acid-d4, sodium salt
541.3
C 26 H 40 D 4 NNaO 7 S
1000
0.542
Glycocholic-d4 acid
469.33
C 26 H 39 D 4 NO 6
1150
0.571
Deoxycholic acid-d4
396.32
C 24 H 36 D 4 O 4
1650
0.654
Taurodeoxycholic acid-d4, sodium salt
525.3
C 26 H 40 D 4 NNaO 6 S
1000
0.526
Glycodeoxycholic acid-d4
453.34
C 26 H 39 D 4 NO 5
1275
0.578
Chenodeoxycholic acid-d4
396.32
C 24 H 36 D 4 O 4
1150
0.425
Taurochenodeoxycholic acid-d4, sodium salt
525.3
C 26 H 40 D 4 NNaO 6 s
1000
0.526
Glycochenodeoxycholic-d4 acid
453.34
C 26 H 39 D 4 NO 5
3800
1.724
Tauroursodeoxycholic acid-d4, sodium salt
525.3
C 26 H 40 D 4 NNaO 6 S
500
0.263
Glycoursodeoxycholic acid-d4
453.34
C 26 H 39 D 4 NO 5 C 24 H 36 D 4 O 5 C 24 H 36 D 4 O 3
600
0.272
3β,5α,6β-trihydroxycholanoic acid-d4
412.31
250
0.103
lithocholic acid-d4
380.32
250
0.095
Taurolithocholic acid-d4, sodium salt
509.31
C 26 H 40 D 4 NNaO 5 S
250
0.127
Glycolithocholic-acid-d4
437.34
C 26 H 39 D 4 NO 4 C 24 H 36 D 4 O 4 C 24 H 34 D 4 O 3
250
0.109
Ursodeoxycholic acid-d4
396.32
300
0.119
Cholenic acid-d4
378.31
250
0.095
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