SPLASH Brochure

Bile Acid SPLASH ™ Product number 330736

Bile acids have long been known to play important functions in digestion and absorption of lipids. More recently, bile acids have been recognized as important signalling molecules with roles in microbiome homeostasis and metabolic disease. Dysregulation of bile acids can be indicative of various pathologies, making them promising targets of disease research. We created Bile Acid SPLASH so researchers can measure a wide array of bile acids in plasma using one pre-mixed internal standard mixture.

Compound name

Exact mass

Chemical formula

Target conc (µM)

Target conc (µg/mL)

Cholic acid-d4

412.31

C 24 H 36 D 4 O 5

1150

0.474

Taurocholic acid-d4, sodium salt

541.3

C 26 H 40 D 4 NNaO 7 S

1000

0.542

Glycocholic-d4 acid

469.33

C 26 H 39 D 4 NO 6

1150

0.571

Deoxycholic acid-d4

396.32

C 24 H 36 D 4 O 4

1650

0.654

Taurodeoxycholic acid-d4, sodium salt

525.3

C 26 H 40 D 4 NNaO 6 S

1000

0.526

Glycodeoxycholic acid-d4

453.34

C 26 H 39 D 4 NO 5

1275

0.578

Chenodeoxycholic acid-d4

396.32

C 24 H 36 D 4 O 4

1150

0.425

Taurochenodeoxycholic acid-d4, sodium salt

525.3

C 26 H 40 D 4 NNaO 6 s

1000

0.526

Glycochenodeoxycholic-d4 acid

453.34

C 26 H 39 D 4 NO 5

3800

1.724

Tauroursodeoxycholic acid-d4, sodium salt

525.3

C 26 H 40 D 4 NNaO 6 S

500

0.263

Glycoursodeoxycholic acid-d4

453.34

C 26 H 39 D 4 NO 5 C 24 H 36 D 4 O 5 C 24 H 36 D 4 O 3

600

0.272

3β,5α,6β-trihydroxycholanoic acid-d4

412.31

250

0.103

lithocholic acid-d4

380.32

250

0.095

Taurolithocholic acid-d4, sodium salt

509.31

C 26 H 40 D 4 NNaO 5 S

250

0.127

Glycolithocholic-acid-d4

437.34

C 26 H 39 D 4 NO 4 C 24 H 36 D 4 O 4 C 24 H 34 D 4 O 3

250

0.109

Ursodeoxycholic acid-d4

396.32

300

0.119

Cholenic acid-d4

378.31

250

0.095

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