SPLASH Brochure

Ceramide LIPIDOMIX Product number 330712

TM

Ceramides have significant clinical implications with regards to inflammation, immune response, and a variety of diseases. Ceramide LIPIDOMIX was developed to provide a clinically relevant ceramide mixture, and as suc1h it contains several key ceramides shown to be correlated to cardiovascular disease.

Compound name

Exact mass

Chemical formula

Target conc (µM)

Target conc (µg/mL)

C16 Ceramide (d18:1/16:0)

537.512

C 34 H 67 NO 3 C 36 H 71 NO 3 C 42 H 83 NO 3 C 42 H 81 NO 3

30

16.1

C18 Ceramide (d18:1/18:0)

565.543

15

8.5

C24 Ceramide (d18:1/24:0)

649.637

75

48.8

C24:1 Ceramide (d18:1/24:1(15Z))

647.622

37.5

24.3

1 European Heart Journal, Volume 37, Issue 25, 1 July 2016, Pages 1967–1976, https://doi.org/10.1093/eurheartj/ehw148

SPLASH II Product number 330709 TM

SPLASH II is a variation on the original SPLASH designed for plasma lipidomics. Modifications include the addition of plasmalogens and the removal of cholesterol, PG, PA, and MAG.

Compound name

Exact mass

Chemical formula

Target conc (µM)

Target conc (µg/mL)

15:0-18:1(d7) PC

752.61

C 41 H 73 D 7 NO 8 P C 38 H 67 D 7 NO 8 P

210

158.2

15:0-18:1(d7) PE

710.56

7

5

15:0-18:1(d7) PS (Na Salt)

776.53

C 39 H 66 D 7 NNaO 10 P C 42 H 75 D 7 NO 13 P C 26 H 45 D 7 NO 7 P

10

7.8

15:0-18:1(d7) PI (NH4 Salt)

846.6

10

8.5

18:1(d7) Lyso PC

528.39

45

23.80

1.0

18:1(d7) Lyso PE

486.35

C 23 H 39 D 7 NO 7 P

0.50

18:1(d7) Chol Ester

657.64

C 45 H 71 D 7 O 2

530

348.80

C18(Plasm)-18:1(d9) PC

780.67

C 44 H 77 D 9 NO 7 P

10

7.80

15:0-18:1(d7) DAG

587.55

C 36 H 61 D 7 O 5 C 51 H 89 D 7 O 6

20

11.80

15:0-18:1(d7)-15:0 TAG

811.77

70

56.90

d18:1-18:1(d9) SM

737.64

C 41 H 72 D 9 N 2 O 6 P C 41 H 71 D 9 NO 7 P

40

29.50

C18(Plasm)-18:1(d9) PE

738.62

0.1

0.07

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