SPLASH Brochure

Mouse SPLASH TM Product number 330710

Ceramide LIPIDOMIX TM Product number 330712

Mouse SPLASH TM is similar to the original SPLASH TM , but with concentrations based on the lipid composition of murine samples.

Ceramides have significant clinical implications with regards to inflammation, immune response, and a variety of diseases. Ceramide LIPIDOMIX TM was developed to provide a clinically relevant ceramide mixture, and as suc1h it contains several key ceramides shown to be correlated to cardiovascular disease.

Compound name

Exact mass

Chemical formula Target conc (µM)

Target conc (µg/mL)

Compound name

Exact mass

Chemical formula

Target conc (µM)

Target conc (µg/mL)

15:0-18:1(d7) PC

752.61

C 41 H 73 D 7 NO 8 P C 38 H 67 D 7 NO 8 P

100

75.3

C16 Ceramide (d18:1/16:0)

537.512

C 34 H 67 NO 3 C 36 H 71 NO 3 C 42 H 83 NO 3 C 42 H 81 NO 3

30

16.1

15:0-18:1(d7) PE

710.56

7

5

C18 Ceramide (d18:1/18:0)

565.543

15

8.5

15:0-18:1(d7) PS (Na Salt)

776.53

C 39 H 66 D 7 NNaO 10 P C 39 H 67 D 7 NaO 10 P C 42 H 75 D 7 NO 13 P C 36 H 61 D 7 NaO 8 P C 26 H 45 D 7 NO 7 P C 23 H 39 D 7 NO 7 P

20

15.5

C24 Ceramide (d18:1/24:0)

649.637

75

48.8

15:0-18:1(d7) PG (Na Salt)

763.54

5

3.8

C24:1 Ceramide (d18:1/24:1(15Z))

647.622

37.5

24.3

15:0-18:1(d7) PI (NH4 Salt)

846.6

20

16.9

15:0-18:1(d7) PA (Na Salt)

689.5

10

6.9

1 European Heart Journal, Volume 37, Issue 25, 1 July 2016, Pages 1967–1976, https://doi.org/10.1093/eurheartj/ehw148

18:1(d7) Lyso PC

528.39

45

23.8

18:1(d7) Lyso PE

486.35

2

1

SPLASH TM II Product number 330709

18:1(d7) Chol Ester

657.64

C 45 H 71 D 7 O 2

250

164.5

C18(Plasm)-18:1(d9) PC

780.67

C 44 H 77 D 9 NO 7 P

20

15.6

15:0-18:1(d7) DAG

587.55

C 36 H 61 D 7 O 5 C 51 H 89 D 7 O 6

15

8.8

15:0-18:1(d7)-15:0 TAG

811.77

35

28.4

d18:1-18:1(d9) SM

737.64

C 41 H 72 D 9 N 2 O 6 P C 41 H 71 D 9 NO 7 P

20

14.8

SPLASH TM II is a variation on the original SPLASH TM designed for plasma lipidomics. Modifications include the addition of plasmalogens and the removal of cholesterol, PG, PA, and MAG.

C18(Plasm)-18:1(d9) PE

738.62

5

3.7

Compound name

Exact mass

Chemical formula

Target conc (µM)

Target conc (µg/mL)

15:0-18:1(d7) PC

752.61

C 41 H 73 D 7 NO 8 P C 38 H 67 D 7 NO 8 P

210

158.2

15:0-18:1(d7) PE

710.56

7

5

15:0-18:1(d7) PS (Na Salt)

776.53

C 39 H 66 D 7 NNaO 10 P C 42 H 75 D 7 NO 13 P C 26 H 45 D 7 NO 7 P

10

7.8

15:0-18:1(d7) PI (NH4 Salt)

846.6

10

8.5

18:1(d7) Lyso PC

528.39

45

23.80

18:1(d7) Lyso PE

486.35

C 23 H 39 D 7 NO 7 P

1

0.50

18:1(d7) Chol Ester

657.64

C 45 H 71 D 7 O 2

530

348.80

C18(Plasm)-18:1(d9) PC

780.67

C 44 H 77 D 9 NO 7 P

10

7.80

15:0-18:1(d7) DAG

587.55

C 36 H 61 D 7 O 5 C 51 H 89 D 7 O 6

20

11.80

15:0-18:1(d7)-15:0 TAG

811.77

70

56.90

d18:1-18:1(d9) SM

737.64

C 41 H 72 D 9 N 2 O 6 P C 41 H 71 D 9 NO 7 P

40

29.50

C18(Plasm)-18:1(d9) PE

738.62

0.1

0.07

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14

15

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