SPLASH™ BOOSTER Product number 330740-1EA
New product
Concentration (µg/mL)*
Compound name
Molecular weight
Exact mass
Chemical formula
15:0-18:1 (d7) PA (Na Salt)
689.927
689.499
C 36 H 61 D 7 NaO 8 P C 31 H 56 D 7 NO 3 C 39 H 68 D 7 NO 8 C 45 H 78 D 7 NO 13
5.4
C13-dihydroceramide-d7 (d18:0-d7/13:0)
504.88
504.52
1.0
C15 Glucosyl (B) Ceramide-D7 (d18:1-D7/15:0)
693.06
692.59
4.2
C15 Lactosyl (B) Ceramide-d7 (d18:1-D7/15:0)
855.21
854.65
5.6
Oleic acid-d9
291.517
291.312
C 18 H 25 D 9 O 2
4.5
*Concentrations are based on the isotopic purity of each individual compound
MSI SPLASH ™ Product number 330841
As the role of lipids in neurodegenerative diseases such as Parkinson’s Disease is increasingly acknowledged, it has become essential to consider what lipids may have a hand in neuropathology. MSI SPLASH is made specifically for Mass Spec Imaging of neurological tissue. The mixture of thirteen internal standards is designed to be applied to brain sections using a sprayer, similarly to the application of matrix for MALDI. MSI SPLASH allows not only for quantitation of lipids within the brain, but also localization of those lipids to provide more detailed information for answering biological questions. This mixture was designed in collaboration with Michiel Vandenbosch, Shadrack Mutuku, Shane Ellis & Kim Ekroos. Toward Omics-Scale Quantitative Mass Spectrometry Imaging of Lipids in Brain Tissue Using a Multiclass Internal Standard Mixture. Michiel Vandenbosch, Shadrack M. Mutuku, Maria José Q. Mantas, Nathan H. Patterson, Tucker Hallmark, Marc Claesen, Ron M. A. Heeren, Nathan G. Hatcher, Nico Verbeeck, Kim Ekroos, and Shane R. Ellis. Analytical Chemistry 2023 95 (51), 18719-18730 DOI: 10.1021/acs.analchem.3c02724
Compound name
Exact mass Chemical formula Target conc (µM)
Target conc (µg/mL)
15:0-18:1 (d7) PA
689.499
C 39 H 69 D 5 NaO 10 P C 41 H 73 D 5 NaO 10 P C 43 H 73 DD 5 NaO 10 P C 45 H 75 DD 5 NaO 10 P C 37 H 64 D 5 NNaO 10 P C 39 H 68 D 5 NNaO 10 P C 41 H 72 D 5 NNaO 10 P C 43 H 72 D 5 NNaO 10 P C 45 H 74 D 5 NNaO 10 P
159.44
0.11
15:0-18:1 (d7) PE
710.559
140.64
0.1
15:0-18:1 (d7) PG
763.536
64.14
0.049
15:0-18:1 (d7) PI
846.596
27.15
0.023
17:0-16:1 PS-d5
774.52
135.48
0.105
17:0 Lyso PE-d5
472.33
6.35
0.003
C12 Mono-sulfo galactosyl(beta) ceramide (d18:1/12:0)
740.486
25.64
0.019
C15 Lactosyl(beta) ceramide-d7 (d18:1/15:0)
854.65
15.2
0.013
C18 Ceramide-d7 (d18:1/18:0)
572.587
19.2
0.011
C17 Glucosyl(beta) Ceramide (d18:1/18:0)
713.581
C 34 H 59 D 5 O 5 C 36 H 63 D 5 O 5 C 38 H 67 D 5 O 5 C 40 H 67 D 5 O 5
186.26
0.133
SM d18:1/18:1(d9)
737.64
42
0.031
17:0 Lyso PC-d5
514.38
5.83
0.003
15:0-18:1 (d7) PC
752.606
213.79
0.161
5
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