Pallotta 2012 | Anti-inflammatory
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Pallotta RC, Bjordal JM, Frigo L, Leal Junior EC, Teixeira S, Marcos RL, Ramos L, Messias Fde M, Lopes-Martins RA. Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation. Lasers Med Sci. 2012 Jan;27(1):71-8.
- Design : animal laboratory study (30 Whistar rats) - Methods : knee joint inflammation was induced with - Results : - Significant reduction of the number of leucocytes and neutrophils in the joint cavity - Significant reduction of pro-inflammatory mediators (IL-1, IL-6) implicated in cartilage degeneration
KEY MESSAGE: The results suggest that laser radiation could be acting to modulate the inflammatory process and possibly to stimulate the production of anti-inflammatory mediators.
Pubmed
iEnovis
Fig. 1 Analysis of articular wash 3 and 6 h after induced inflammation. a Total number of leukocytes in articular lavage fluid after 3 h in the control group and after LLLT (n=6 animals per group (*p<0.05) (**p<0.001). b Total number of leukocytes in articular lavage fluid after 6 h in the control group and after LLLT (n=6 animals per group arthritis group (AT); the arthritis group treated with diclofenac (Diclof); the arthritis group treated with 1 J LLLT (AT+ 1 J); the arthritis group treated with 3 J LLLT (AT+3 J); the arthritis group treated with 6 J LLLT (AT+6 J); the arthritis group treated with 10 J LLLT (AT+10 J). Results are expressed as mean (±SEM)
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