Gao 2009 | Tissue repair
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Gao X, Xing D. Molecular mechanisms of cell proliferation induced by low power laser irradiation. J Biomed Sci. 2009; 16(1): 4.
This study discusses the discovered mitochondrial photoacceptors and nonmitochondrial photoacceptors, and then reviews the studies on the molecular mechanisms of LPLI-induced proliferation since January 1999, which will serve as a reference for the researchers in this field - A number of signalling proteinsare involved with laser-induced cell proliferation. - Laser irradiation can regulate cell cycle progression by by the activation or elevated expressions of cell cycle-specific proteins. - Laser irradiation reduces signal molecules involved in inflammatory response and enhances immunomodulatory effects. - Laser irradiation induces expression and secretion of growth factors, interleukins, inflammatory cytokines and small molecules (such as ATP, ROS, intracellular Ca 2+ ).
Molecular mechanisms of LPLI induced cell proliferation involve a number of signalling proteins, cell cycle-specific proteins and other molecules such as growth factors, interleukins, inflammatory cytokines and other small molecules.
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