Photobiomodulation Clinical Evidence

Ahmad 2022 | Knee OA

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Ahmad MA, A Hamid MS, Yusof A. Effects of low-level and high-intensity laser therapy as adjunctive to rehabilitation exercise on pain, stiffness and function in knee osteoarthritis: a systematic review and meta-analysis. Physiotherapy. 2022 Mar;114:85-95.

Systematic review and Meta-analysis including10 studieswith high PEDRO score for methodological quality. • 6 investigated LLLT + Exercise, • 3 on HILT + Exercise, and • 1 evaluated both. Results Based on the meta-analysis of the scores on the VAS and WOMAC subscales: • HILT + E combination demonstrated larger effects compared to control for knee pain, stiffness and function scores. • LLLT + E combination showed small effects for knee pain and function. • Comparatively, HILT + E showed a change of 2.06 points for VAS, which is clinically significant, whereas LLLT + E only achieved a change of 0.67 points for the same measures.

KEY MESSAGE: Photobiomodulation therapy, compared to control, is an effective adjunct treatment modality for improving pain, stiffness and function in knee OA, with HILT producing larger effects than LLLT.

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