Photobiomodulation Clinical Evidence

Song 2020 | Knee OA

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Song HJ, Seo HJ, Kim D. Effectiveness of high-intensity laser therapy in the management of patients with knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials. J Back Musculoskelet Rehabil. 2020;33(6):875-884.

Systematic review and Meta-analysis Results : • 6 randomized controlled trials (RCTs) were included in this meta-analysis. • For VAS pain , 334 patients from 4 studies showed that HILT significantly decreased pain compared to the control (MD, -1.18; 95% CI, -1.68 to -0.69). • For stiffness , 168 patients from 4 studies showed that HILT significantly improved WOMAC stiffness compared to the control (SMD -1.00; 95% CI -1.32, -0.68) • For function , 87 patients from 4 studies showed that HILT significantly improved function compared to the control(SMD, -5.36; 95% CI -7.39 to -3.34).

KEY MESSAGE: HILT can significantly improve pain, stiffness and function in Knee Osteoarthritis compared to placebo or other control interventions.

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