Chatterjee 2019 | Diabetic Neuropathy
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Chatterjee P, Srivastava AK, Kumar DA, Chakrawarty A, Khan MA, Ambashtha AK, Kumar V, De Taboada L, Dey AB. Effect of deep tissue laser therapy treatment on peripheral neuropathic pain in older adults with type 2 diabetes: a pilot randomized clinical trial. BMC Geriatr. 2019 Aug 12;19(1):218.
Randomized double-blind sham-controlled trial. - Subjects : 40 patients with type 2 diabetes with painful diabetic peripheral neuropathy - HILT group: HILT + standard care - Control group: sham laser + standard care - 2x/wk for 4 weeks + 1x/wk for 8 weeks (12 weeks in total) - Device : LightForce HPL device (810/980 nm) - HILT protocol: - Treatment area: plantar foot and lumbar region (DRG L4-S2) - Power: plantar 2W; lumbar 8W - Energy density: plantar 1.8-3.0 J/cm²; lumbar 13 J/cm² - Total dose: plantar 300-1800 J; lumbar 1920 J - Application technique: on contact scanning technique - Results - Signif. more pain relief in HILT group - Greater improvements of function HILT group - Signif. improvement of QoL in HILT group vs. no improvement in control group - Serum levels of inflammatory biomarkers improved more in the HILT group
KEY MESSAGE: HILT is a safe, nonpharmacological addition to the standard of care for the management of pain in older adults with painful diabetic peripheral neuropathy, offering significant improvement of their quality of life.
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