Chow 2011 | Analgesia
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Chow R, Armati P, Laakso EL, Bjordal JM, Baxter GD. Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review. Photomed Laser Surg. 2011 Jun;29(6):365-81.
Systematic review . • 44 studies were suitable for inclusion, 18 human and 26 animal studies.
Results : •
Chow et al. 2011 | Analgesia
In 13 of 18 human studies, pulsed or continuous wave visible and continuous wave infrared (IR) laser irradiation slowed conduction velocity (CV) and/or reduced the amplitude of compound action potentials (CAPs). • Human studies further support the hypothesis that inhibition of conduction velocity requires higher doses of laser irradiation. • In 26 animal experiments, IR laser irradiation suppressed electrically and noxiously evoked action potentials including pro-inflammatory mediators.
KEY MESSAGE: The evidence supports the view that neural inhibition is a plausible mechanism for the relief of acute and chronic pain with LLLT. Pubmed iEnovis
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