How are Neuroendocrine Cancers formed? Neuroendocrine cancer, (known medically as malignant neuroendocrine neoplasm or NEN), was first described as a specific disease in the mid-1800’s. In 1907, the term ‘Carcinoid’ was applied – from the German word for “cancer-like”. This term became very popular amongst the medical community of the time, as it was believed that neuroendocrine cancer behaved very differently to common cancers. It was thought that all neuroendocrine cancers were very indolent, that is, very slow growing and unlikely to spread or behave in the same way as other malignancies. However, 20 years later, Obendorfer revised his view, concluding that ‘carcinoids’ could indeed behave like other cancers, albeit at different growth rates.
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