NCUK Virtual Patient Handbook

By examining genes we can see how certain traits (such as eye ne generation to the next. mutation:

the development of a health condition

family members

t gene that might make a treatment more or less likely to be effective

n chemotherapy drugs (e.g., 5FU or Capecitabine) worse or even an be undertaken before these drugs are given. Capecitabine is

UK website HERE at target NTRK fusion-positive solid tumours: such as Entrectinib and

TRK3, which produce TKR proteins help regulate cell signalling

gether and producing altered TRK proteins, sion-positive tumours are rare (less than 1% in common our types, including breast, cholangiocarcinoma, colorectal, mall cell lung, salivary gland, pancreatic, sarcoma and thyroid

on 12 August 2020) available at https://www.nice.org.uk/guidance/ta644 d on 27 May 2020) available at https://www.nice.org.uk/guidance/ta630)

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