NCUK Virtual Patient Handbook

Is Neuroendocrine Cancer genetic? Most neuroendocrine cancers occur ‘sporadically’, this means that there is no known genetic (inherited) link to how or why they have developed. However, there are a number of rare inherited genetic conditions that may increase someone’s risk of developing a neuroendocrine cancer, these include: • Multiple Endocrine Neoplasia MEN types 1-4 • Familial medullary thyroid cancer (FMTC) • Familial phaeochromocytoma +/- paraganglioma (Adrenal gland related tumours) • Parathyroid hyperplasia

• Familial isolated pituitary adenoma (FIPA) • Succinate dehydrogenase (SDH) disorders

• Von-Hippel Lindau • Neurofibromatosis 1

Click here to listen to the Not Just NE Cancer podcast, with Jo Grey, CEO of AMEND

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