Research and Science
The MRF Breakthrough Consortium (MRFBC) is a unique national network of 33 academic centers of excellence in melanoma. The MRFBC fosters collaboration and information exchange to accelerate the research and development of the most promising therapies in melanoma treatment in order to deliver curative options to patients. MRFBC institutions have a track record of receiving NIH/peer-reviewed funding, publications in major medical journals, presentations at major cancer and melanoma conferences, clinical trial expertise and patient care. An in-person MRFBC meeting was held at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
2025 MRFBC Team Award Funding support enables the annual MRFBC Team Award. In 2025, the MRFBC Team Award was granted to a team of scientists investigating RNA-LNP therapeutics for melanomas resistant to current treatments, particularly immunotherapy. The multi-disciplinary research team is led by Ravi Amaravadi, MD of the University of Pennsylvania.
Huntsman Cancer Institute
University of Colorado
Mayo Clinic*
Northwestern University University
Dana Farber/Harvard Cancer Center Yale University
of Chicago Ohio State University
Cornell University
Memorial Sloan Kettering Cancer Center Columbia University
University of Pittsburgh
California Pacific Medical Center
New York University
University of California San Francisco
Northwell Health University of Pennsylvania/ Wistar Institute
Ravi Amaravadi, MD
Stanford Cancer Institute
Fox Chase Cancer Center
Thomas Jefferson University
St. John’s Cancer Institute
Georgetown-Lombardi Comprehensive Cancer Center University of Virginia Johns Hopkins University
The Angeles Clinic and Research Center
Duke University
University of California Los Angeles
University of North Carolina
MD Anderson Cancer Center
University of Arizona
Moffitt Cancer Center
Vanderbilt University
University of Miami
* Includes satellite sites in Arizona and Florida. Note: New sites added in 2025: University of Virginia, University of North Carolina, Cornell University, Stanford Cancer Institute, University of Arizona and Mayo Clinic (Rochester, MN and satellite sites in Phoenix, Arizona and Jacksonville, Florida).
8 • Stewardship Report
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