SF3B1 MT MDS-RS at the Single Cell Level
Ineffective erythropoiesis
Ringed Sideroblasts
SF3B1 MT
We profiled the hematopoietic landscape of SF3B1 MT MDS-RS at the single-cell level
Lin - CD34 + HSPCs
BM-MNCs
Ery
SF3B 1 MT Lin - CD34 + HSPCs:
Ery
Increased Ery/Mk differentiation Metabolic activation in SF3B1 -mutant cells
Increased Erythroblast at the Orthochromatic stage SF3B 1 MT MNCs:
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