Cancer testis antigen and interleukin expression correlates…

MD Anderson

SBNET

3

Transcriptional analysis revealed a distinct subset of patients who were high in cancer testis antigen and interleukin expression

Unsupervised clustering into CT Antigen hi and interleukin hi groups formed the same cohort of 8 patients (6 of 8 had metastatic disease)

PRAME (PReferentially expressed Antigen in MElanoma) is one of the mostwidelystudiedcancer testis antigens with tumor-specific expression across multiple tumor types

CTA/IL High (n=8)

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