?(&1.0&#.! Psychodynamic interpersonal therapy (PIT) consisted of 12 weekly sessions, which were specifically adapted to the needs of patients with bodily distress. Conceptually, our approach assumes that developmentally based dysregulations of (bodily) self-experience and relationships rather than unconscious conflicts are the primary basis for the symptoms. PIT was compared with an Enhanced Medical Care group, which received education and counselling regarding the therapeutic alternatives based on the evidence-based guidelines for the treatment of somatoform disorders/functional somatic syndromes in primary and somatic specialist care. Both treatments were manualized and the adherence of the therapists was determined for all therapeutic sessions. ;&2-5.2! As primary outcome we prespecified a clinically relevant improvement in bodily quality of life (as compared to the control group). Our findings suggest that this improvement can be achieved using a short-term intervention consisting of 12 PIT sessions in patients, who experience chronic and disabling bodily symptoms that have no recognised treatment. The success of the treatment was independent of the patients’ bodily symptom characteristics of each patient, so that PIT was suited to improve bodily quality of life in patients with a multitude of different chronic physical symptoms. So far additional analyses related to our study addressed economic aspects of PISO, attachment styles, functional MR-imaging studies and the use of heart rate variability in order to predict therapy outcome. These studies are published or underway. Trial registration: International Standard Randomised Controlled Trial Number ISRCTN23215121. G$#.1/.! Prof. Dr. med. Peter Henningsen p.henningsen@tum.de Department of Psychosomatic Medicine and Psychotherapy, Klinikum Rechts der Isar, Technische Universität München Langerstr. 3 D-81675 Munich
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