Open Door Review

Intent-to-treat analyses were performed in a twofold way: observed cases (OC) as well as last observation carried forward (LOCF). In addition completer analyses were conducted. ;&2-5.2! In the TFP group significantly fewer drop-outs occurred (38.5% v. 67.3%) and also significantly fewer patients attempted suicide (d = 0.8, P = 0.009). TFP was significantly superior with regard to borderline symptomatology (d = 1.6, P = 0.001), psychosocial functioning (d = 1.0, P = 0.002), personality organisation (d = 1.0, P = 0.001) and psychiatric in-patient admissions (d = 0.5, P = 0.001). Both groups improved significantly in the realm of depression and anxiety and the transference- focused psychotherapy group in general psychopathology, all without significant group differences (d = 0.3–0.5). Self-harming behaviour did not change in either group. Moreover, improvement in RF was significantly greater in the TFP group as compared with the ECP group. The effect was of medium size (d = 0.45). Attachment status improved significantly in the TFP group, but not in the ECP group: Twelve out of 38 TFP patients available for follow-up changed from insecure to secure attachment status, whereas none did so in the ECP group. The coherence scale improved strongly in the TFP group (effect size d=1.27) and just moderately in the ECP group (d=0.32). OC analyses revealed similar results as LOCF analyses with higher effect sizes and lower levels of significance. Completer analyses with control for treatment dose remained significant for GAF score, DSM-IV criteria for BPD, and personality organization. G$#/5-2*$#! TFP is an efficacious psychoanalytic psychotherapy for the treatment of patients with borderline personality organization. ?(*15!(&Y*2.(1.*$#!

Clinical trials.gov: NCT00714311.

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Professor Stephan Doering, M.D. Chair of the Dept. of Psychoanalysis and Psychotherapy, Medical University of Vienna Währinger Gürtel 18-20, A-1090 Wien, Austria Phone: +43-1-40400-25190/-30610, Fax: +43-1-406 68 03 Email: stephan.doering@meduniwien.ac.at, www.meduniwien.ac.at/hp/psychoanalyse/

CVP

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