8#2*D06!$*!3%2$*!:B*7($)*6!$*!7#%)*$7!&01%0660&!12($0*(6!2:(0%!<)*DE (0%9!1647#)2*2<4($7!7)912%0&!Z$(#!7)D*$($Y0!30#2Y$)B%2
L$67#92**!"_!5B66!@>N>!2*&!A0BC$*D0%EF)#<030%!@>![+,-P^?!"%2B92_!&%029!2*&!1647#$7!7#2*D0!$*! 1647#)2*2<4606?!2!&$2<)DB0!30(Z00*!1647#)2*2<46$6!2*&!(#0!*0B%)67$0*706>! Q#"+,)%#(&)+&9>$@+&0%>#" 67$0*70_! d_!bdd>!&)$?!-,>PPb\u:*#B9>+,-P>,,bdd>! L$67#92**_!">_!A0BC$*D0%EF)#<030%_!@>_!IJ7#0<0_!H>![+,-+^?!"%2B9:)%67#B*D!$*!&0%!/647#)2*2<460?!I<$*$67#0! Q(B&$0*_!"%2B960%$0*_!0c(%2M<$*$67#0!L)%67#B*D!$9!A23)%>!/647#0_!gg_!bPPEbg->! A0BC$*D0%EF)#<030%_!@>_! Q)(?-$@++O&1C ![+,-]^?!"%2*6D0*0%2($)*0<<0!K0$(0%D230!Y)*!"%2B92!B*&!O01%066$)*?! /647#)2*2<4($67#0!B*&!01$D0*0($67#0!Å30%<0DB*D0*>!;*?!V>!ABc!G!">!5$7#(0%![H%6D>^?!IB<(B%0*!&0%!'1$D0*0($M?! V0%0%3(_!7)&$0%(_!T30%(%2D0*>!F0%<$*?!O0S%B4(0%_!Q>!g\Ebb> & The FRED started in 2007 and is a still ongoing study conducted at the Sigmund-Freud-Institut in cooperation with the research team of the LAC-depression study, the Brain Imaging Center (BIC) and the Max-Planck-Institute for brain research (MPIH) in Frankfurt, the Hanse Neuro-Psychoanalysis study (HNPS) and the sleep-somnological centre of the hospital Hofheim. The research is funded by the Neuro-Psychoanalysis Society – HOPE and the Research Advisory Board of the IPA. W1/RY($-#'!!! Depression from a brain physiological angle may be related to a neurotransmitter disorder, or a frontal lobe dysfunction (Belaker & Agam, 2008; Caspi et al., 2003; Risch et al., 2009). It may also be the result of a disturbed “reward system” (Northoff & Hayes, 2011). But despite these findings no distinct brain physiological marker for depression has been found so far. 4'20&&;443&&32D.2E&&F&&19.3;&&2;.1.40&&GHIJ&&F& NPV
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