Vital Highlights 2014-2021

FUNDING FLAGSHIP 3 ( 2016 - 2020 )

Sydney Vital : $ 671 , 454

External Sources : $ 1 , 580 , 454

Item 1 29.8%

Item 2 34.7%

33.2%

Item 1 65.3%

66.8%

Item 2 70.2%

External Sources include : CINSW , Cancer Council NSW , NHMRC , Ramsay Foundation , and CSSANZ

RESEARCH SUCCESSES

Obtained two patents : X - ray triggered chemotherapy and PCT based on our liposome - CRISPR delivery technology . Developed a program about X - ray - triggered photodynamic therapy ( X - PDT ) demonstrating for the first time improved rectal cancer survival in mice with X - PDT delivered via engineered nanocarriers made from a clinically approved polymer . Developed a theranostic magnetic nano - platform for non - invasively detecting , diagnosing and eliminating lymph node metastases . Developed a model for colorectal polyp development , understand risk of lymphnode metastasis in very early ( malignant polyp ) colorectal cancer and enhance polyp recognition using nano - optonics ( close collaboration with Colorectal TCE and Prof Mark Molloy ). Demonstrated the efficacy of X - ray triggered chemotherapy in colorectal cancer .

P A G E

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