APAF ( MACQUARIE UNIVERSITY )
The Australian Proteome Analysis Facility has 20 years ’ experience as a one - stop provider for many protein - based analysis methods . We specialise in mass spectrometry , protein separation by chromatography and electrophoresis , amino acid analysis by HPLC , bead - based ELISA and bioinformatics .
For cancer research we have expertise
to
analyse circulating biomarkers , analyse tumour tissues or cell line lysates . We can analyse conditioned culture media and immunoprecipitations to find novel protein - protein interactions . We can monitor signal transduction networks to plasma / serum for examine effects of stimuli or inhibitors by conducting phosphoproteomic mapping . We are also investigating the role of protein glycosylation in cancer .
Proteomic analysis plot A new area of research is in the quantitation of cancer drug pharmacokinetics using high resolut ion mass spectrometry in support of improved patient dosing to avoid toxicity or under - dosing
Find out more about APAF here .
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