Expert neonatologists at Riley Children’s Health deliver specialized, evidence- based care to neonates in need of lifesaving services. In many cases, our care begins prenatally and continues through the transition to home with comprehensive, multidisciplinary follow-up in the Riley Early Years Program. NEONATOLOGY
RESEARCH HIGHLIGHTS
Major clinical studies ■ POPS – Studying the pharmacokinetics,
pharmacodynamics and safety profile of understudied drugs administered to children per standard of care ■ TPN Biobank – Studying intestinal failure-associated liver disease through a biorepository of blood and urine samples ■ STAR – Evaluating the safety, tolerability and efficacy of RLS-0071 in newborns with moderate or severe hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia (Phase II study) ■ PLaNT – Evaluating the feasibility of performing a trial that compares use of early prophylactic CPAP with no CPAP among late preterm infants born via Cesarean (international multicenter study) ■ Salt to Grow – Hypothesizing that implementing a sodium supplementation algorithm will improve in- hospital somatic growth ■ AT-100 – Evaluating the safety and tolerability profile of AT-100 (rhSP-D) in preterm neonates at high risk for developing BPD Advanced technologies and procedures ■ Rapid whole genome sequencing ■ Therapeutic hypothermia ■ Continuous EEG monitoring ■ Neonatal dialysis ■ Miris human milk analyzer: Novel device measures nutritional content in breast milk ■ Riley NICU Twistle Program: Only NICU virtual communication platform in the nation that uses automated workflows that optimize parent engagement and safer transition to home. In addition to being selected as a study site for the potential National Institutes of Health ARISING study (U01 grant under review), Riley Children’s aims to improve outcomes with more than 10 research, quality improvement and clinical projects targeting at-risk patients, end-stage kidney disease and more.
DIVISION CHIEF Laura S. Haneline, MD Edwin L. Gresham Professor of Pediatrics, IU School of Medicine > Connect with Dr. Haneline on Doximity.
PROGRAM DISTINCTIONS
Specialized programs Fetal Center
Fetal surgery program includes fetoscopic laser for twin- to-twin transfusion syndrome, radiofrequency ablation for twin reversed arterial perfusion, chest and bladder shunts, and percutaneous umbilical blood sampling. The Fetal Center managed 466 referrals in 2023—13 from outside Indiana. The center is engaged in two North American Fetal Therapy Network (NAFTnet) data registries and two NAFTnet research trials. Riley Heart Center NICU Model of shared management between neonatology, cardiac intensivists and cardiology is executed by less than 10% of centers. *** We are developing a national database focused on the care of neonates with critical congenital heart disease. Bronchopulmonary Dysplasia (BPD) Program Program improves the outcomes of patients with severe BPD throughout their NICU stay and as outpatients during their early years. > READ more about our BPD program. NeuroNICU Targeted surveillance, evidence-based treatment options and support provided to more than 250 newborns each year. In 2023, our team developed a neuroprotective bundle guideline for infants less than 32 weeks gestation. Neonatal Kidney Health Program This program for neonates with acute kidney injury expanded in 2023 to 10 providers with expertise in
■ Ranked among the leading neonatology programs in the nation by U.S. News & World Report ■ Home to one of the first neonatal neurocritical care units in the nation (established in 2013) ■ Innovative heart center NICU with complete integration and daily team rounding of neonatologists with CV intensivists and cardiologists that contribute to excellent outcomes ■ ECMO program designated a Platinum Level Center of Excellence by the Extracorporeal Life Support Organization Riley Children’s, home to a Level IV NICU, is 6th out of 47 U.S. centers * in the number of comorbidities present on admission, reflecting the complexity of our NICU patient population. Quality care and patient safety Riley Neonatology is in the top centile for fewest number of babies who are under the 10th percentile for weight upon hospital discharge. **
55 board certified physicians
See full team member list >
NOTABLE PUBLICATIONS New England Journal of Medicine: February 2023 Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth Pediatrics: March 2023 Sleep Apnea in Children with Down Syndrome The Journal of Pediatrics: May 2023 Genetic Testing Guidelines Impact Care in Newborns With Congenital Heart Defects Journal of Child Neurology: April 2023 A Standardized, 3-Tiered, Seizure Burden-Based Protocol for the Treatment of Neonatal Seizures World Journal for Pediatric and Congenital Heart Surgery: June 2023 Perioperative Care Models for Neonates
neonatal kidney health and dialysis. Riley Perinatal Genomics Program One in four NICU patients receives rapid genome sequencing. > READ about our comprehensive
with Congenital Heart Disease: Evolving Role of Neonatology
Length of stay is reduced by half for
99 research publications in 2023
NICU patients receiving genetic testing at Riley Children’s. (Compared to historical controls and regardless of test result)
Within the Cardiac Intensive Care Unit
genomics program for critically ill newborns.
* Children’s Hospitals Neonatal Consortium database ** Vermont Oxford Network *** Children’s Hospitals Neonatal Consortium survey
Annual Report 2022 – 2023
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