Riley Children's Health Annual Report 2023 – 2024

The pediatric nephrologists at Riley Children’s Health are leaders in using novel technologies and research breakthroughs to launch new clinical programs that lead to better treatments for children impacted by kidney disease. Our nephrology specialists provide comprehensive evaluation and treatment for children with kidney disease or kidney failure. NEPHROLOGY RANKED 10 TH IN THE NATION

RESEARCH HIGHLIGHTS

■ 26 active clinical studies ■ In 2023: – 2 National Institutes of Health (NIH) R01 grants awarded –1 NIH K23 career development grant awarded ■ Member of the Pediatric Nephrology Research Consortium , participating in the international CureGN (with high enrollment and retention) and HIKO-STEC studies ■ Long-standing participant in the Chronic Kidney Disease in Children (CKiD) study and the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

DIVISION CHIEF David S. Hains, MD, MBA Byron P. & Francis D. Hollett Professor of Pediatrics, IU School of Medicine > Connect with Dr. Hains on Doximity.

PROGRAM DISTINCTIONS

Specialized programs Metabolic Bone Disease Program

■ Ranked among the top 10 pediatric nephrology programs in the nation by U.S. News & World Report

For patients with chronic nephrolithiasis and low bone mineral density, we focus on identifying risk factors, accurately diagnosing osteoporosis with the use of pediatric densitometry, and establishing a protocol for medication treatment options. Neonatal Acute Kidney Injury (AKI) Program

10 board certified physicians

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See full team member list

■ 12th pediatric center in the nation to launch aquapheresis

Leader in kidney transplants

Our population of post- kidney transplant patients has increased from 88 in 2019 to 141 in 2024. Launched in 2021, the Pediatric Kidney Transplant Transition Program at Riley Children’s currently follows 42 patients.

NOTABLE PUBLICATIONS

Recognition of AKI in the NICU has

■ Riley Children’s ranks within the first quartile nationally in pediatric kidney transplant volume and is among the top centers in patient outcomes. ■ We are a longtime

■ Home to the first comprehensive neonatal kidney health program; includes both inpatient consultations and outpatient care ■ Offers ambulatory blood pressure monitoring (ABPM) for patients with asymptomatic elevated blood pressure; completes more than 400 24-hour ABPM readings annually ■ Home to a comprehensive multidisciplinary pediatric kidney transplant program incorporating pediatrics and internal medicine, nephrology, adolescent medicine, and psychology

Our neonatal AKI surveillance and consultation program— one of the few in the nation—captures all neonates with an AKI

JAMA Network Open: August 2023 Acute Kidney Injury Defined by Fluid- Corrected Creatinine in Premature Neonates: A Secondary Analysis of the PENUT Randomized Clinical Trial PLoS One: May 2023 Psychosocial Supports Within Pediatric Nephrology Practices: A Pediatric Nephrology Research Consortium Survey Pediatric Nephrology: June 2023 Safety and Timeliness of Telemedicine Initiation of Continuous Kidney Replacement Therapy Pediatric Nephrology: September 2023 Using Aquapheresis with Continuous Hematocrit Monitoring to Guide Ultrafiltration American Journal of Kidney Diseases: March 2023 Racial and Ethnic Disparities in Acute Care Utilization

improved from 17% to 100% and decreased the rate of AKI.

episode and delivers streamlined outpatient follow-up and research study enrollment. 24-Hour Ambulatory Blood Pressure Monitoring Program and ABPM First Patients with elevated blood pressure readings and/or their providers have access to a rapid visit involving a 24-hour ambulatory blood pressure monitor before a full clinic consultation. Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Program Patients are seen by specialists from nephrology, urology, and medical and molecular genetics during

member of the Improving Renal Outcomes Collaborative . ■ Quality improvement initiatives: Improving medication adherence, reducing length of stay and readmissions

High hemodialysis volume Riley Nephrology provides outpatient care for 40 to 50 patients and performs more than 1,200 days of renal replacement on an inpatient basis each year.

a single visit that occurs monthly. Young Adult Transition Program

Designed for 16- to 26-year old patients with chronic kidney disease, this program focuses on ensuring a smooth transition to adult healthcare providers.

Riley Children’s has the only comprehensive pediatric dialysis unit serving children in Indiana. We provide inpatient (including NICU and PICU) and acute hemodialysis and peritoneal dialysis services.

49 research publications in 2023

Among Patients with Glomerular Disease

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Annual Report 2023 – 2024

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