Highly trained neurologists at Riley Children’s Health use the latest tools and therapies to diagnose and treat the most complex neurologic disorders in children. Our team, which includes 17 pediatric neurologists, five advanced practice providers and a genetic counselor, manages numerous specialized multidisciplinary services, including programs for muscular dystrophy and refractory epilepsy. NEUROLOGY
RESEARCH HIGHLIGHTS
■ Translational epilepsy research to identify molecular targets for novel treatments ■ Translational research grant to study the effects of new migraine therapies on bone health ■ Clinical trials for spinal muscular atrophy and muscular dystrophies ■ Evaluation of cholinergic markers in children with and without autism and Fragile X syndrome ■ Research of a wearable device to better understand sudden unexpected death in epilepsy NOVEL EPILEPSY RESEARCH Makram M. Obeid, MD, studies the mechanisms of epileptogenesis in immature animal seizure models. The primary goal is to identify molecular targets for novel treatment strategies that can prevent seizures and the accompanying neurodevelopmental behavioral deficits.
DIRECTOR Christopher T. Jackman, MD Associate Professor of Clinical Neurology, IU School of Medicine > Connect with Dr. Jackman on Doximity.
PROGRAM DISTINCTIONS
Specialized programs Comprehensive Epilepsy Program NEW Riley Children’s is one of the few centers in the Midwest to offer magnetoencephalography. The technology expands the scope of care for patients with refractory epilepsy and improves surgical evaluations. Also for epilepsy, our team offers: ■ Multispecialty, collaborative epilepsy surgery program with Riley Neurosurgery ■ Stereo EEG monitoring, SPECT and PET to localize seizure foci ■ Team of experts with dedicated epileptologists, neuropsychologists, radiologists, dietitians and geneticists Neurogenetics Program Through our comprehensive program, specially trained physicians and genetic counselors help families understand complex inherited genetic neurologic conditions.
■ Ranked among the leading pediatric neurology and neurosurgery programs in the nation by U.S. News & World Report ■ Muscular Dystrophy Association Care Center, recognizing clinical care and research; Parent Project Muscular Dystrophy Certified Duchenne Care Center ■ One of the few centers in the nation performing gene therapy for Duchenne muscular dystrophy and spinal muscular atrophy
17 board certified physicians
See full team member list >
NOTABLE PUBLICATIONS Pediatric Neurology: May 2023 Role of Early Intravenous Immunoglobulins in Halting Clinical and Radiographic Disease Progression
Epilepsy Volume and Patient Outcomes: 2023
920 new patients
1,406 standard EEGs
in Rasmussen Encephalitis Journal of Child Neurology: December 2023
■ Accredited by the National Association of Epilepsy Centers as a Level 4 epilepsy center
Pediatric Cluster Headache Case Series: Symptomatic Cases and the Migraine Relationship Journal of Child Neurology: March 2023 A Standardized, 3-Tiered, Seizure Burden–Based Protocol for the Treatment of Neonatal Seizures Journal of Child Neurology: March 2023 Tolerability and Safety of Lacosamide in Neonatal Population Epilepsy Research: July 2023 Lestaurtinib (CEP-701) Reduces the Duration of Limbic Status Epilepticus in Periadolescent Rats
1,245 unique patients undergoing prolonged EEG
771 admissions
■ Member of a unique clinical program for patients with Pelizaeus-Merzbacher disease; clinic held yearly for patients from across the U.S.
to the epilepsy monitoring unit
■ Pompe disease program offering genetics and physical therapy
The EEG laboratory and the long-term EEG monitoring program at Riley Children’s are accredited by ABRET Neurodiagnostic Credentialing and Accreditation. Our program produces: ■ High rates of seizure freedom with leading-edge laser ablations or surgical resections ■ High rates of seizure control using the latest neuromodulation techniques (RNS, DBS, VNS)
Other specialized programs ■ Pediatric Headache Center ■ Cerebral Palsy Program ■ NICU Follow-up Program ■ Neurofibromatosis Program ■ Neurogenetics Program
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Annual Report 2023 – 2024
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