The neuroradiology program at Riley Children’s Health provides leading-edge imaging and interpretation for the expert diagnosis of irregularities of the brain and spine. Our pediatric neuroradiologists and neurointerventional radiologists collaborate with multiple pediatric clinical specialties to help ensure the highest levels of care for infants, children and adolescents with a variety of diseases and conditions of the head and neck, brain, and spine. NEURORADIOLOGY
RESEARCH HIGHLIGHTS
Riley neuroradiologists serve as principal investigators or principal site investigators for several National Institutes of Health (NIH)-funded studies. ■ NIH-funded study evaluating maternal brain function in prenatal opioid exposure ■ Assessment of brain structure, function and neurocognition in adults with congenital heart disease Riley Neuroradiology received a $3.1 million multicenter grant from the NIH to study fetal brain growth and placental function in pregnant women with prenatal opioid exposure. Our radiologists serve as collaborators on these other studies (funded by both NIH and other organizations): ■ Study on understanding brain effects of cerebral malaria in children in Uganda ■ Research studies on mechanical thrombectomy and hematoma evacuation in intracranial clots and neuroendovascular devices Other clinical research ■ Accuracy of radiography, CT and MRI in evaluation of spine fractures in children evaluated for abuse ■ Quantitative brain volume and cortical parametric analysis for identification of epileptogenic regions in epilepsy ■ Inner ear malformations in children with Treacher Collins syndrome ■ Radiogenomics of craniofacial malformations
DIRECTOR Rupa Radhakrishnan, MD, MS Associate Professor of Radiology and Imaging Sciences, IU School of Medicine > Connect with Dr. Radhakrishnan on Doximity.
PROGRAM DISTINCTIONS
Riley Children’s is one of the few facilities in the Midwest offering comprehensive pediatric functional MRI for presurgical eloquent cortex mapping. This technique identifies regions of the brain that are involved in motor, language or visual functions prior to brain
■ Only group of trained pediatric neuroradiologists in Indiana
6 board certified physicians
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■ Provides leading-edge neuroimaging techniques –High-field strength 3 Tesla (T) magnetic resonance imaging (MRI) –Diffusion tensor imaging and tractography for neurosurgical planning – Pediatric brain functional MRI for brain mapping –Brain perfusion imaging –Vascular imaging, including magnetic resonance angiography, magnetic resonance venography and vessel wall imaging –Magnetic resonance spectroscopy for metabolite assessments –Dynamic cerebrospinal fluid (CSF) flow imaging –Protocols for fast brain imaging and imaging without anesthesia in young infants –Rapid stroke imaging –Low radiation dose computed tomography (CT) imaging protocols ■ Wide range of imaging-guided pediatric spine interventional services (lumbar puncture, myelograms, biopsies, patching for CSF leaks)
NOTABLE PUBLICATIONS Pediatric Blood and Cancer: January 2023 Successful Isavuconazole Salvage Therapy for Cerebral Mucormycosis in a Child With Relapsed Leukemia: A Light in the Dark Tunnel World Neurosurgery: March 2023 Single-Institution Comparative Study of Magnetic Resonance-Guided Laser Interstitial Thermal Therapy and Open Corpus Callosotomy Journal of Neurosurgery: December 2023 Safety and Efficacy of Endovascular Versus Microsurgical Treatment of Unruptured Wide-Necked Middle Cerebral Artery Aneurysms: A Propensity Score-Matched Analysis of the NeuroVascular
surgery to prevent damage to important brain structures.
Neuroradiology Volume: 2019 – 2023 Cross-sectional imaging studies (CT and MRI)
14,638
13,644 13,793
12,564
11,237
Quality Initiative Quality Outcomes Database Cerebral Aneurysm Registry
■ Only site in Indiana with an intra-arterial chemotherapy program for retinoblastoma
12 research publications in 2023
■ Dedicated pediatric neuroradiology fellowship program
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Annual Report 2023 – 2024
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