The pediatric nephrologists at Riley Children’s Health are leaders in using novel technologies and research breakthroughs to launch new clinical programs that lead to better treatments for children impacted by kidney disease. Our nephrology specialists provide comprehensive evaluation and treatment for children with kidney disease or kidney failure. NEPHROLOGY
Professional organization affiliations
RESEARCH HIGHLIGHTS
Global clinical trials leader
■ National Institutes of Health (NIH)-funded
CHAIR, SECTION OF NEPHROLOGY American Academy of Pediatrics > Amy C. Wilson, MD MEMBER, BOARD OF DIRECTORS Pediatric Nephrology Research Consortium > Myda Khalid, MD VICE CHAIR, UTI CLINICAL PRACTICE GUIDELINE COMMITTEE American Academy of Pediatrics > David S. Hains, MD, MBA CO-CHAIR, PEDIATRICS ACADEMIC SOCIETIES PROGRAM COMMITTEE American Society of Pediatric Nephrology > Danielle E. Soranno, MD MEMBER, EXECUTIVE BOARD Neonatal Kidney Collaborative > Michelle C. Starr, MD MEMBER, EXECUTIVE COUNCIL Midwest Society for Pediatrics Research > Michelle C. Starr, MD
Enrolling the world’s first pediatric participant in
CureGN study – Enrolled 32 participants in this multicenter trial targeting glomerulonephropathy ■ Chronic Kidney Disease in Children (CKiD) study site since 2005 (funded by NIH) ■ Riley investigator-initiated program that combines clinical care of glomerular nephritis patients with research in one clinic. ■ Coordinating center for AWAKEN 2 (Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0) with 15,000 infants enrolled in more than 100 centers in 36 countries.
PIONEER , Riley Children’s is leading this first-of-its-kind international multisite clinical trial to combat immunoglobulin A nephropathy, a disease with limited treatment options. PIONEER is a Phase II study to evaluate the safety and efficacy of atacicept in autoimmune glomerular diseases. Riley Children’s enrolled the first patient in the U.S. in the EMPA Kidney Kids global clinical trial to study the safety and efficacy of empagliflozin in children with chronic kidney disease.
Committed to quality and patient safety
TOP DISTINCTIONS
2025 statistics
Riley
SCOPE * target
■ Multidisciplinary Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Program; facilitates care for more than 100 patients a year ■ Home to the nation’s first comprehensive neonatal kidney health program; includes both inpatient consultations and outpatient care ■ Offers ambulatory blood pressure monitoring (ABPM) for patients with asymptomatic elevated blood pressure; completes more than 400 24-hour ABPM readings annually ■ Home to a comprehensive multidisciplinary pediatric kidney transplant program incorporating pediatrics and internal medicine, nephrology, adolescent medicine and psychology
0.12 0.25
0.25
Peritoneal dialysis exit site infections
Hemodialysis exit site and tunnel infections
0.40
Annualized rate (episodes/patient year) * Standardizing Care to Improve Outcomes in Pediatric End-Stage Kidney Disease Collaborative
1,200
1,152
1,130
1,058
Continuous Renal Replacement Therapy (CRRT) Program Volume: 2017 – 2025
688
538
488
59 research publications in 2025
357
313
NOTABLE PUBLICATIONS
Pediatrics: July 2025 Perinatal urinary tract dilation: Recommendations on pre-/postnatal imaging, prophylactic antibiotics, and follow-up: Clinical report Pediatric Nephrology: April 2026 “Why won’t the ammonia go down?”: Ammonia management while on continuous kidney replacement therapy Pediatric Nephrology: September 2025 Hyperglycemia and kidney outcomes in critically ill children and young adults on continuous kidney replacement therapy Scientific Reports: October 2025 Digital droplet PCR is an accurate and precise method to measure DNA copy number Clinical Journal of the American Society of Nephrology: April 2025 Proteinuria trajectory and disease progression in children and adults with IgA nephropathy/vasculitis
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Driving improvements in patient care
Riley Children’s has the only comprehensive pediatric dialysis unit serving children in Indiana. We provide inpatient (including NICU and PICU) and acute hemodialysis and peritoneal dialysis services.
Next-level enhancements in inpatient continuous renal replacement therapy (CRRT) at Riley Children’s are contributing to improved acute kidney care in the ICU. Telemedicine initiation of CRRT makes it easier to get renal replacement up and running quickly. > Learn more.
DIVISION CHIEF David S. Hains, MD, MBA Byron P. & Francis D. Hollett Professor of Pediatrics, IU School of Medicine > Connect with Dr. Hains on Doximity.
11 board certified physicians
See full team member list >
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