Spleen
Largest single mass of lymphatic tissue in the body. Located between the stomach and diaphragm efferent lymphatic vessels pass through the spleen Parenchyma consists of 2 types of lymphatic tissue:
White Pulp : lymphatic tissue consisting mainly of lymphocytes, and macrophages Red Pulp : consists of blood-filled venous sinuses and cords of splenic tissue called Splenic Cords (AKA Billroth’s). These cords consist of RBCs, macrophages, lymphocytes, plasma cells, and granulocytes. Blood flowing into the spleen through the splenic artery enters the white pulp where B and T cells carry out immune functions similar to lymph nodes, while spleen macrophages destroy blood-borne pathogens by phagocytosis. Red pulp removes ruptured, worn out, or defective blood cells and platelets, store platelets (up to 1/3 of the body’s supply) and produces blood cells (hemopoiesis) during fetal life.
Lymphatic Nodules
Egg-shaped masses of lymphatic tissue NOT surrounded by a capsule. Scattered throughout CT of mucus membranes lining the GI tract, urinary tract, reproductive tracts, and respiratory airways. Also referred to as Mucosa-Associated Lymphatic Tissue (MALT).
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