Longevity Medical Institute FAQ's

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What is the first-pass lung effect in stem cell IV treatments, and how does LMI address it? The first-pass effect occurs when a portion of stem cells, administered intravenously, becomes temporarily trapped in the lungs due to their size. While this may reduce the number of cells reaching other tissues initially, it’s not necessarily a bad thing. The lungs are one of the most critical organs for oxygenating your blood and supporting tissue health. The stem cells play a vital role in repairing and regenerating lung tissue, addressing any underlying issues or inflammation. At LMI, we recognize this as an added benefit, as healthier lung function directly enhances overall oxygen delivery and systemic recovery. Additionally, LMI’s advanced protocols are designed to optimize stem cell distribution, ensuring therapeutic benefits to both the lungs and other target tissues, maximizing the regenerative potential.

At LMI, we mitigate some of the first-pass effect using several proprietary strategies:

Oxygen supplementation during infusion improves oxygenation and reduces lung inflammation, helping the cells circulate more effectively.

Slower administration of stem cells minimize the risk of lung entrapment, allowing more cells to bypass the lungs and reach target areas.

Nutraceuticals that act as natural vasodilators, which help improve blood flow and reduce lung entrapment, further enhancing cell circulation.

Exosome therapy is also employed, as exosomes are smaller and bypass lung entrapment, providing a powerful addition to whole cells.

These approaches significantly improve the efficacy and safety of our stem cell treatments.

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