MEDICAL MUSHROOMS AND THEIR ROLE IN REINFORCING THE IMMUNE SYSTEM
Reishi polysaccharides have demonstrated to enhance the immune system 1,2
Clearance of HPV 16 and 18 after oral supplementation during 2 months with medical mushrooms 3 Medical mushrooms in oral HPV control
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90 80 70 60 50 40 30 20 10 0
88%
5% Control (n=41)
Reishi + C. versicolor (n=20)
P<0.001
Polysaccharides Activate the humoral and cellular immunity 1,2,4
Polysaccharides
• B cell and T cell proliferation • Monocyte activation • Natural killer cell activation • Increase in interleukin production
• Increase in IFN α production
1. Lin, Zhi-Bin. “Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum.” Journal of pharmacological sciences vol. 99,2 (2005): 144-53. doi:10.1254/jphs.crj05008x 2. Xu, Zengtao et al. “Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities.” The American journal of Chinese medicine vol. 39,1 (2011): 15-27. doi:10.1142/S0192415X11008610 3. Donatini, Bruno. “Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial.” International journal of medicinal mushrooms vol. 16,5 (2014): 497-8. doi:10.1615/intjmedmushrooms.v16.i5.80 4. Chan, Godfrey Chi-Fung et al. “The e ects of beta-glucan on human immune and cancer cells.” Journal of hematology & oncology vol. 2 (2009) 25. doi:10.1186/1756-8722-2-25
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