HR HPV PERSISTENCE IS A NECESSARY CONDITION TO DEVELOP HIGH GRADE LESIONS 1
Viral persistence 2,3
10 20% 21%
LSIL
HPV+
HSIL
48% 35%
Modi able factors associated with clearance and regression of HPV-dependent lesions
Balance of the vaginal microbiota 6
Local immune response 7
Lifestyle 8
Reepithelialisation of the cervical transformation zone 4,5
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