Chen et al. 2020
Back to overview
Chen Z, Chen ZY, Liu WH, Li GS. Electric Stimulation as an Effective Adjunctive Therapy for Diabetic Foot Ulcer: A Meta-analysis of Randomized Controlled Trials. Adv Skin Wound Care. 2020 Nov;33(11):608-612.
Design: Systematic review and meta-analysis • including randomized clinical trials published through March 2019 that compared the efficacy of ES and standard wound care (SWC) versus SWC alone for DFU treatment. Outcomes included: Percentage decrease in ulcer area at 4 weeks (4w- PDUA) as assessed by image-recording; Healing rate at 12 weeks. Results: • Of the 145 randomized clinical trials initially identified, 7 studies (with a total of 274 patients) met the inclusion criteria. • The studies used BP pulsed current, HVPC, low intensity direct current • The percentage decrease in ulcer area at 4 weeks was significantly greater in patients treated with ES and SWC than SWC alone (standardized mean difference = 1.09 (95% CI, 0.62 – 1.57; P < .001; I2 = 67%) • The ulcer healing rate at 12 weeks was also significantly faster in the ES group (risk difference = 0.19 (95% CI, 0.06 – 0.32; P = 0.005; I2 = 0%)
Key message: This meta-analysis demonstrates that ES may accelerate DFU healing and be an effective adjunctive therapy for these complex wounds.
iEnovis
Pubmed
37
© 2022 Enovis Corporation
CONFIDENTIAL
Made with FlippingBook - PDF hosting