Diabetic Ulcer Research O/V

Melotto et al. 2022

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Melotto G, Tunprasert T, Forss JR. The effects of electrical stimulation on diabetic ulcers of foot and lower limb: A systematic review. Int Wound J. 2022 Nov;19(7):1911-1933.

Design: Systematic Review • Inclusion criteria consisted of individuals with type 1 or type 2 DM with foot and/or lower limb ulceration, with any diabetic ulcer aetiology, that is, neuropathic, ischaemic and neuro-ischaemic, and were treated with Electrical Stimulation (ES). Outcomes included: Results were narratively synthetized. Results: • 7 articles met the inclusion criteria. • The studies used BP pulsed current, HVPC, low intensity DC • 3 articles were classified as high quality, whilst 4 studies are considered as moderate or low quality. • Findings showed that healing rate appears to be higher among diabetic ulcers treated with ES; however, the reliability of these findings is affected by the small sample sizes of the studies. • Two studies conducted by the same authors presented a statistically significant healing rate improvement (P < .05) after 4 weeks of direct current ES intervention by comparing the percentage of healing rate between the intervention group and the control group.

Key message: Electrical stimulation is probably more effective than SWC alone on DFUs in terms of healing rate. In particular, Direct Current electrical stimulation has demonstrated encouraging effects on healing rate of ischaemic DFUs. However, the evidence to suggest the systematic usage of ES in the treatment of DFUs is still insufficient.

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