Melanoma Research Foundation Research Portfolio
The Melanoma Research Foundation (MRF) is the leading non-profit organization dedicated to eradicating melanoma by accelerating medical RESEARCH , while EDUCATING to and ADVOCATING for the melanoma community.
Funding Melanoma Research
The MRF provides emerging and established scientific investigators (from medical students to senior investigative teams) with highly sought-after, peer-reviewed grants across the disciplines of biology, immunology, prevention, diagnosis and treatment. From 1998 to 2020, the MRF grant program has awarded 200 grants at 75 institutions to investigators at all stages in their career paths, totaling over $18.8 million.
GRANTS FUNDED AT 75 INSTITUTIONS
TYPES OF GRANTS FUNDED:
TYPES OF GRANTS PURPOSE
Introduces students early in their careers to clinical/research opportunities under
Medical students at an accredited U.S. medical school or institution
the mentorship of an investigator engaged in melanoma research
Enables young researchers to generate the groundwork that can leverage additional grant funding from other funding bodies
Junior investigators which include: • Postdoctoral fellows with less than five years of postdoctoral experience OR • A research associate, instructor, assistant professor or the equivalent
Encourages proven researchers to continue research on emerging challenges in melanoma
Established researchers, mainly faculty with at least an associate professor appointment
Encourages collaboration across academic disciplines in an institution or among multiple institutions
A PI and at least one co-PI, ideally from different institutions
Fosters clinical trials in the melanoma space
Junior through established investigators
T he MRF grant was instrumental in helping us to advance our melanoma research program and to connect with the melanoma community.
T his grant was the first one I was awarded after finishing my medical training, and tremendously helped establish my academic career.
Creation of Resources MRF BREAKTHROUGH CONSORTIUM (MRFBC)
Recognizing a need for greater collaboration around translational research, the MRF formed the MRFBC in 2010. The MRFBC is a national network of 20 centers of excellence in melanoma that collaborate to accelerate drug development.
University of Colorado Northwestern University University
of Chicago Ohio State University
University of Pittsburgh
California Pacific Medical Center
Dana Farber/Harvard Cancer Center Yale University Memorial Sloan Kettering Cancer Center Columbia University New York University University of Pennsylvania/ Wistar Institute Georgetown-Lombardi Comprehensive Cancer Center
University of California San Francisco
City of Hope
The Angeles Clinic and Research Center
University of California Los Angeles
M.D. Anderson Cancer Center
Virtual Repository A Virtual Specimen Repository has been established with harmonized SOPs to ensure consistency across institutions and trials and over time. Rare Subtype Focus Community United for Research and Education of Ocular Melanoma (CURE OM) In 2011, the MRF launched CURE OM to focus solely on advancing the goals of the ocular melanoma community. To date, CURE OM has provided $2 million in research grants, held numerous scientific meetings and is launching a patient registry while continuing to advocate for the ocular melanoma community to improve the lives of people impacted by this disease. Pediatric and Mucosal/Acral Lentiginous Melanoma Initiatives The MRF has also launched initiatives that focus on pediat- ric and mucosal/acral lentiginous (MM/ALM) melanoma. As such, the MRF is supporting grants focused on pediatric melanoma as well as mucosal melanoma. With respect to pediatric melanoma, the MRF sponsors an Annual Pediatric
Moffitt Cancer Center
Summit each year so that families can come together and learn the latest in medical treatments and research, and find support. With respect to MM/ALM, the MRF is providing funding support for a biomarker trial for MM/ALM patients. Support to the Field • Partnership with the Society for Melanoma Research to sponsor annual investigator awards and satellite symposia • Scientific meetings such as the Brain Metastases Summits 1.0 and 2.0 and the State of Melanoma. The MRF will host the Brain Metastases Summit 3.0 in 2021. • In 2019, the MRF awarded Humanitarian Awards to four physicians in the melanoma community at galas in Chicago, Philadelphia, Denver and New York City Further, due largely to patient suggestions, the MRF has developed a wide array of educational information, downloads for use in the office, links to clinical trials, buddy programs and online support groups. More information about the MRF, its programs and its scientific leadership can be found at www.melanoma.org. Patient Perspective Incorporating a patient-centric approach to the grant review process, a patient review panel ensures that patient and caregiver priorities are reflected in the research funding process.
FUNDING FROM THE MRF HAS RESULTED IN:
22 CLINICAL TRIALS
83 GRANTS WITH NEW COLLABORATIONS
51 GRANTS WITH NEW FUNDING SUPPORT
69 MEDICAL STUDENT AWARDS
31 ESTABLISHED INVESTIGATOR AWARDS
89 CAREER DEVELOPMENT AWARDS
11 TEAM AWARDS
TO LEARN MORE, VISIT MELANOMA.ORG/RESEARCH-SCIENCE
MELANOMA RESEARCH FOUNDATION melanoma.org/research-science 202.347.9675 or 800.673.1290Page 1 Page 2 Page 3 Page 4
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