Comprehensive 140+ Lab Panel: Longevity Medical Institute

What We Measure and Why It Matters! At Longevity Medical Institute, our Comprehensive Longevity Biomarker Panel evaluates more than 140 biomarkers across cardiovascular health, metabolic function, hormonal balance, thyroid health, nutritional status, inflammation, immune activity, infectious disease screening, autoimmune activity, digestive and fecal health, organ performance, coagulation health, oncology-related biomarkers, and biological aging. Rather than reviewing isolated laboratory values, our physicians interpret these biomarkers as an integrated system to identify hidden risks, biological imbalances, and opportunities for optimization before they become clinically significant. By evaluating multiple physiological systems simultaneously, we can detect patterns associated with cardiovascular disease, metabolic dysfunction, chronic inflammation, hormone imbalance, immune dysregulation, nutritional deficiencies, accelerated aging, and early disease risk. Featured Biomarkers for Healthy Aging While every biomarker contributes valuable information, several markers have emerged as particularly important indicators of cardiovascular health, metabolic resilience, inflammation, hormone balance, and healthy aging. Apolipoprotein B (ApoB) Measures the number of potentially artery-forming lipoprotein particles and is considered one of the strongest predictors of cardiovascular disease risk. Lipoprotein(a) [Lp(a)] A genetically inherited cardiovascular risk marker associated with heart attack, stroke, and aortic valve disease. High-Sensitivity C-Reactive Protein (hs-CRP) A highly sensitive marker of systemic inflammation linked to cardiovascular disease, metabolic dysfunction, neurodegeneration, and accelerated aging. Homocysteine An amino acid involved in methylation pathways that has been associated with cardiovascular disease, cognitive decline, and impaired cellular repair. Insulin One of the earliest indicators of metabolic dysfunction and insulin resistance, often becoming abnormal years before glucose levels rise. HOMA-IR An estimate of insulin resistance that helps identify metabolic dysfunction and diabetes risk before traditional markers become abnormal. Insulin-Like Growth Factor-1 (IGF-1) A growth factor involved in tissue maintenance, muscle preservation, recovery, and healthy aging. NT-proBNP A cardiac stress marker released by the heart that may help identify early cardiovascular strain and dysfunction. Vitamin D A critical nutrient involved in immune function, bone health, hormone balance, cardiovascular health, and longevity. Testosterone A key hormone supporting muscle mass, metabolic health, cognitive performance, energy levels, sexual wellness, and healthy aging. Dehydroepiandrosterone Sulfate (DHEA-S) An adrenal hormone often used as a marker of vitality, resilience, hormonal reserve, and healthy aging. Thyroid Function Evaluated through TSH, T3, T4, Free T3, Free T4, thyroid antibodies, and related markers that regulate metabolism, energy production, body composition, and overall cellular function. These featured biomarkers represent only a portion of the more than 140 laboratory measurements included within our Comprehensive Longevity Biomarker Panel. Together, they help provide a detailed picture of cardiovascular health, metabolic function, inflammation, hormonal balance, biological aging, and overall wellness.

COMPREHENSIVE LONGEVITY BIOMARKER PANEL

Understanding what your body is telling you — one integrated picture of cardiovascular health, metabolism, hormones, inflammation, and biological age.

140+ BIOMARKERS MEASURED Across sixteen physiological systems, evaluated together rather than in isolation, to reveal hidden risks and opportunities for optimization before they become clinically significant.

Cardiovascular

Metabolic

Hormonal

Thyroid

Nutritional

Inflammation

Immune

Infectious Disease

Autoimmune

Coagulation

Liver & Pancreas

Kidney

Urinalysis

Digestive

Oncology

Hematology

Biological Aging

Longevity Medical Institute What We Measure & Why It Matters

FEATURED MARKERS FOR HEALTHY AGING The Signals That Matter Most

ApoB One of the strongest predictors of cardiovascular disease risk. Lipoprotein(a) Inherited risk marker for heart attack, stroke, and aortic valve disease. hs-CRP Sensitive marker of systemic inflammation and accelerated aging. Homocysteine Methylation marker tied to cardiovascular and cognitive health. Insulin & HOMA Index Among the earliest signs of metabolic dysfunction, often years early. IGF-1 Growth factor for tissue repair, muscle preservation, and recovery.

NT-proBNP Cardiac stress marker flagging early cardiovascular strain. Vitamin D Immune, bone, hormonal, and cardiovascular health. Testosterone & DHEA-S Hormones of vitality, muscle, cognition, and resilience. Cortisol Stress hormone affecting sleep, metabolism, immunity, and cognition. Thyroid Panel TSH, T3, T4, free fractions & antibodies governing metabolism. Lp-PLA2 Enzyme flagging active inflammation within the arterial wall.

HOW WE USE THEM A Systems View of Your Health

No single laboratory value determines health. Our physicians read these biomarkers as one interconnected system — identifying patterns that reveal hidden cardiovascular risk, metabolic dysfunction, hormone imbalance, nutritional deficiencies, immune activation, chronic inflammation, and early disease processes. By evaluating multiple physiological systems at once, we can detect issues before they become clinically significant, personalize treatment, and track your progress over time.

COMPLETE TEST MENU Every Test We Offer

A combined panel for all patients. Markers noted (male) or (female) are included based on clinical relevance. ■ Hematology — Complete Blood Count ■ Glucose Metabolism / Diabetes

Erythrocytes (Red Blood Cells) · Hemoglobin · Hematocrit · MCV, MCH, MCHC · Red Cell Distribution Width (RDW) · Platelets & Mean Platelet Volume (MPV) ·

Glucose · Insulin · HOMA Index · Glycated Hemoglobin (HbA1c) ·

■ Inflammation Markers

hs-CRP · Interleukin-6 (IL-6) ·

■ White Blood Cell Differential

■ Kidney Function

Leukocytes (Total WBC) · Lymphocytes (% & absolute) · Monocytes (% & absolute) · Eosinophils (% & absolute) · Basophils (% & absolute) · Segmented Neutrophils (% & absolute) · Band Neutrophils (% & absolute) ·

Urea · Blood Urea Nitrogen (BUN) · Creatinine · Glomerular Filtration Rate (GFR) · Uric Acid ·

■ Liver & Pancreatic Function

Total, Direct & Indirect Bilirubin · AST · ALT · GGT · ALP · LDH · Total Proteins · Albumin · Globulin · Amylase · Lipase ·

■ Additional Hematology

■ Lipid Profile & Cardiovascular Risk Total, HDL, LDL & VLDL Cholesterol · Triglycerides · Atherogenic Index · Apolipoprotein A1 · Apolipoprotein B · Lipoprotein(a) · Lp-PLA2 · NT-proBNP · D-Dimer · Creatine Phosphokinase (CPK) · Erythrocyte Sedimentation Rate (ESR) · Blood Group and Rh Factor ·

■ Electrolytes & Minerals

Sodium · Potassium · Chloride · Magnesium · Phosphorus · Calcium ·

■ Iron Metabolism

Serum Iron · Ferritin ·

COMPLETE TEST MENU — CONTINUED Hormones, Screening & More

■ Hormonal Profile

■ Infectious Disease

Total & Free Testosterone · Estradiol · DHEA-S · DHEA ·

Lyme: Anti-Borrelia IgG & IgM · EBV: EBNA IgG, VCA IgG, VCA IgM ·

■ Autoimmune Studies

Dihydrotestosterone (DHT) · SHBG (reagent being sourced) · Luteinizing Hormone (LH) · Follicle-Stimulating Hormone (FSH) · Prolactin · Progesterone ·

Antinuclear Antibodies (ANA IFA) · Rheumatoid Factor ·

■ Coagulation

Prothrombin Time (PT) · International Normalized Ratio (INR) ·

■ Thyroid Panel TSH · Total T4 & T3 ·

aPTT / PTT · Fibrinogen ·

Free T4 (FT4) & Free T3 (FT3) · T-Uptake · Free Thyroxine Index · Protein-Bound Iodine · Anti-TPO & Anti-Thyroglobulin Ab ·

■ Urinalysis — Physical-Chemical

Color · Appearance · Specific Gravity · pH · Glucose · Bilirubin · Ketones · Proteins ·

Hemoglobin · Urobilinogen · Nitrites · Leukocyte Esterase ·

■ Other Hormones & Aging

Cortisol · IGF-1 (Somatomedin C) ·

■ Urinalysis — Microscopic

Leukocytes · Pus Cells · Erythrocytes · Epithelial Cells · Bacteria · Yeasts · Mucus Filaments · Casts · Crystals ·

■ Vitamins

Vitamin D (25-OH) · Vitamin B12 · Homocysteine ·

■ Digestive Health

Fecal Occult Blood ·

■ Oncology / Tumor Markers

Total & Free PSA, Free PSA Index (male) · Beta-hCG (male) · CA-125 (female) · CA 15-3 (female) · Carcinoembryonic Antigen (CEA) · Alpha-Fetoprotein (AFP) · CA 19-9 Antigen ·

SHBG is subject to reagent availability and may require additional lead time.

At Longevity Medical Institute, our physicians interpret these biomarkers as an interconnected system to support long-term health, performance, resilience, and healthy aging. Tumor markers and screening tests are interpreted alongside medical history, advanced imaging, and physician assessment — no single laboratory value diagnoses disease on its own.

Longevity Medical Institute San José del Cabo, Mexico · longevity-institute.com

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