1 Table of contents 12

Coldkeepers Brochure 2026

Temperature		1
Control,		1
Engineered.		1
When a bridge collapses, everyone notices. When a power grid fails, it dominates headlines.		3
But when a biologic arrives at 11°C instead of 8°C, nothing looks broken.		3
The box appears intact. The label reads correctly. The contents feel cool to the touch. And yet the product inside may already be compromised.		3
Domestic Manufacturing as Risk Mitigation		3
Corrugated Cardboard Box		4
• A one-stop shop/single-source supplier opportunity • High-quality and available in 8, 10, 12 and 14 cube • Coldkeepers branded and keeps continuity with our liners		4
“We have a global patent on one-piece construction. All six sides of a box are completely sealed. There’s no thermal gaps.”		5
For healthcare systems and emergency response agencies, that speed matters. Domestic production shortens lead times, reduces freight volatility, and supports surge deployment when hurricanes, wildfires, or grid failures disrupt regional supply chains. n disaster conditions, temperature-controlled packaging becomes part of public health protection.		5
“In a disaster, it’s twofold,” Griffin explains. “One, to maintain food safety and medication safety.		5
And then the second part is getting much-needed food, much-needed medication to the site safely.”		5
Medication degradation is not visible.		5
Eliminating the Thermal Gap		6
“Most pharmaceuticals have to stay between 2°C and 8°C,” Griffin says. “Reaching 0°C causes flash freezing. which changes the compound and inhibits the medication, destroying biologics. And the same thing to go above 8°C. It can end up being toxic.”		6
When refrigeration access is compromised and ambient heat intensifies, those parameters become harder to maintain — and far more consequential.		6
Coldkeepers designs around that reality without relying on powered refrigeration systems that add cost and complexity.		6
A defining differentiator for Coldkeepers is its globally patented one-piece construction.		6
Traditional EPS coolers rely on separate lids and multi-piece assemblies. Seams shift. Small inconsistencies accumulate. “We have a global patent on one-piece construction,” Griffin says. “All six sides of a box are completely sealed. There’s no thermal gaps.”		6
By eliminating seam variability, the system stabilizes internal conditions across long-haul routes and changing climates.		6
Performance is validated both in environmental chambers and in field testing.		6
Extreme Insulated Mailers		6
One-Piece Extreme Liners • Cold chain protection for medical supplies • FDA compliant/suitable for 24-48-hour shipments • Use with gel packs or dry ice for extended transit times • Patented one piece design, stores, and ships flat • Premium insulation allows for more payload space by reducing wall thickness		7
“Virtually everything that we manufacture and do is U.S.-based — materials, 90% to 99% of everything we sell is U.S.-made.”		8
“There is no true test other than real-world,” Griffin explains. “If they’re shipping from Phoenix to Washington, D.C., we test it. It’s 110 degrees in Phoenix and 45 degrees in D.C. How does that change the packaging? What do we need to do differently?”		8
The emphasis is not volume — it is control.		8
“It’s not really about the products,” Griffin says. “It’s about the solution.”		8
Cold Chain Is an Exact Science		8
Oversimplification remains one of the industry’s biggest risks. “People think, ‘Oh, I’ve got to keep this cold.’ There’s a lot more to it,” Griffin says. “They think I’ll throw a gel pack in something and it’ll be fine. It doesn’t work that way.” Pack-out configuration requires calculated refrigerant placement, insulation layering, and buffering to prevent flash freezing while		8
Sustainability Without Compromise		9
Cold chain packaging has historically relied on EPS and molded coolers that persist in landfills for centuries.		9
“EPS stays in the landfill for over 500 years,” Griffin says. Coldkeepers developed a curbside recyclable product line built primarily from paper-based insulation with a thin internal moisture barrier.		9
“It is certified by Western Michigan University to be curbside recyclable,” Griffin explains.		9
“It’ll fit in your municipal recycle bin. And it actually outperforms styrofoam.”		9
Performance was not sacrificed.		9
“An inch of our paper insulation will outperform an inch and three quarters of EPS,” he says. “They cost the same, they perform the same. You either want sustainability or you don’t.”		9
Pharmaceutical clients operating under ESG mandates are increasingly choosing recyclable solutions that do not compromise thermal reliability.		9
“It is an exact science,” Griffin says.		9
During extreme heat events — increasingly common across large regions of the U.S. — the margin for error narrows. “Rarely does an event happen and everything’s 65 degrees and sunshine,” Griffin notes. “Usually extreme heat is involved. If you don’t have something engineered and strictly built to keep things cold during that kind of heat, it’s going to be compromised.” Cold chain failure rarely looks dramatic. It looks ordinary.		9
Cold Chain Protection, Engineered.		10
Beyond the Box		10
Patented thermal construction		10
Validated 2°C–8°C performance		10
Expanding insulated mailers		10
Recyclable paper-based options		10
Made in the USA		10
“An inch of our paper insulation will outperform an inch and three quarters of EPS. They cost the same, they perform the same. You either want sustainability or you don’t.”		11
In resilience planning, cold chain packaging is often categorized as logistics. In practice, it is embedded risk control.		11
The difference between 2°C and 8°C may look minor on paper.		11
In the field, it determines whether a shipment can be used or must be discarded. Whether a hospital can proceed with treatment or wait for a replacement. Whether response efforts move forward or stall.		11
Coldkeepers works in that space — where temperature control has to hold.		11
In disaster response, the smallest variables often determine whether a system continues to function.		11
That is not a detail. It is a requirement.		11
When temperature control becomes mission-critical, precision matters.		12
coldkeepers.com		12

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