2024 NSTA New Orleans • EDVOTEK® Workshops

05 - Heavy Metal: Effects of Environmental Toxins on C. elegans

Experimental Results and Analysis Copper, zinc, and cadmium should have a minimal effect on wild-type worms. In contrast, thrash rates in the mutant strain should decrease in the presence of these heavy metals. Zinc and copper can cause significantly slowing in the mutant strain worms while cadmium can cause complete mobility loss within the time frame of this experiments. Below are representa- tive results from in house testing. Exact values will vary.

Heavy Metal - COPPER

Control Solution

Wild Type Thrash Count (30 sec.)

Mutant Strain Thrash Count (30 sec.)

Wild Type Thrash Count (30 sec.)

Mutant Strain Thrash Count (30 sec.)

0 min.

39

38

0 min.

45

38

2 min.

40

38

2 min.

43

36

4 min.

38

10

4 min.

41

38

Heavy Metal - ZINC

Heavy Metal - CADMIUM

Wild Type Thrash Count (30 sec.)

Mutant Strain Thrash Count (30 sec.)

Wild Type Thrash Count (30 sec.)

Mutant Strain Thrash Count (30 sec.)

39

42

44

40

0 min.

0 min.

37

14

39

33

2 min.

2 min.

39

0

37

6

4 min.

4 min.

63

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