S2651
RTT - Patient experience and quality of life
ESTRO 2026
Duangsuphan 2 , Panicha Nualsutha 2 , Nattawat Samranjai 2 , Siriporn Wong 2 1 Radiology , Division of Radiation oncology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. 2 Radiology, Division of Radiation oncology, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society,, Bangkok, Thailand. 3 Radiology , Division of Radiation oncology, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society,, Bangkok, Thailand Purpose/Objective: This study comprised two cohorts. The first assessed patient and radiation therapist (RTT) perspectives on temporary ink skin markings. The second evaluated whether integrating a six-degree-of-freedom (6D) couch could further improve setup accuracy, setup time, IGRT time, and total treatment time when used with marker-less or marker-based workflows. Material/Methods: Questionnaires were completed by 79 breast cancer patients and 29 radiation therapists (RTTs) using a 6- point Likert scale (0 = never to 5 = always). The questionnaire assessed emotional experiences related to temporary skin markings and the level of interest in a marker-less approach. Forty patients were assigned to four setup groups: markers without 6D couch (M), markers with 6D couch (M_6D), marker-less without 6D couch (ML), and marker-less with 6D couch (ML_6D). Setup accuracy, setup time, image-guided radiotherapy (IGRT) time, and total treatment time were compared. Results:
bit” or “very much” on at least one anchor item. TCIs were defined using receiver operating characteristic (ROC) analysis, setting the QLQ-PR25 scales as predictors and using the binary criterion of clinical importance to define positive and negative cases. For each scale, the threshold with the highest Youden's J statistic was selected. Areas under the curve (AUCs) were calculated to assess diagnostic accuracy, that is, each scale’s ability to discriminate between negative and positive cases. Results: A total of 260 patients (mean age 71.2 years) were included in this preliminary analysis. Of these, 143 (55%) were receiving current treatment, and 128 (49%) were treated with curative intent. The most common modalities were radiotherapy (n = 40) and endocrine therapy (n = 62); overlap between different treatment modalities was possible. The proportion of positive cases on the combined anchor ranged from 5.0% for urinary incontinence to 15.8% for hormonal treatment–related symptoms. AUCs were 0.90 for bowel symptoms, 0.87 for urinary symptoms, 0.80 for urinary incontinence, and 0.82 for hormonal treatment-related symptoms, demonstrating excellent discrimination2. TCIs were identified for the QLQ-PR25 scales, with thresholds of 13 for bowel symptoms (sensitivity = 0.80, specificity = 0.83), 35 for urinary symptoms (0.81, 0.80), 50 for urinary incontinence (0.62, 0.98), and 14 for hormonal treatment–related symptoms (0.70, 0.87); scores above each TCI indicate a clinically important problem. Conclusion: The development of TCIs for the QLQ-PR25 symptom scales increases the interpretability of questionnaire results, thereby promoting meaningful use in clinical decision-making and facilitating implementation in Giesinger JM, Loth FL, Aaronson NK, Arraras JI, Caocci G, Efficace F, et al.; EORTC Quality of Life Group. Thresholds for clinical importance were established to improve interpretation of the EORTC QLQ-C30 in clinical practice and research. J Clin Epidemiol. 2020;118:1-8.2. Hosmer DW Jr, Lemeshow S, Sturdivant RX. Applied Logistic Regression. 3rd ed. Hoboken (NJ): John Wiley & Sons; 2013. Keywords: Thresholds for Clinical Importance, PROs routine care. References: 1.
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Patient and Staff Perspective Toward Marker-less Patient Setup Accuracy in Breast Radiotherapy Kitwadee Saksornchai 1 , Puntiwa Oonsiri 2 , Sornjarod Oonsiri 3 , Sakda Kingkaew Kingkaew 3 , Mananchaya Vimolnoch 1 , Jumnong Kumkhwao 3 , Photong
About 90% of both patients and RTTs preferred a
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