S2674
RTT - Patient experience and quality of life
ESTRO 2026
and aerobic exercise program, and four served as controls. QoL was assessed using the EORTC QLQ-C30 at baseline and after three months. No intervention was implemented in the control group. Statistical analysis was performed using SPSS v.25, applying the Wilcoxon signed-rank test to assess within- and between-group differences. Results: The mean age was 53.5 years (range 41–71), and 81.8% were female. The most frequent diagnoses were breast cancer (45.5%) and gynecologic tumors (18.2%), followed by prostate cancer (18.2%), sarcomas (9.1%), and others (9.1%). Most had localized disease (81.8%) and were in complete remission (63.6%).In the exercise group (n = 7), significant improvements were found in overall QoL (Z = –2.384; p = 0.017), physical functioning (Z = –2.388; p = 0.017), daily activities (Z = – 2.388; p = 0.017), cognitive (Z = –2.271; p = 0.023), and social functioning (Z = –2.271; p = 0.023). Fatigue (Z = – 2.060; p = 0.039) and pain (Z = –2.207; p = 0.027) significantly decreased.Trends toward improvement were observed in emotional role (p = 0.066), dyspnea (p = 0.059), and nausea/vomiting (p = 0.063), though not statistically significant. No relevant changes were found in insomnia (p = 0.102), anorexia (p = 0.102), constipation (p = 0.102), diarrhea (p = 0.157), or financial impact (p = 1.000).In contrast, the control group (n = 4) showed no significant differences between baseline and three-month assessments (all p > 0.05). Conclusion: A three-month supervised exercise program improved QoL in patients at different stages of cancer treatment, particularly by reducing fatigue and pain. Incorporating structured exercise interventions within oncology and radiotherapy departments may enhance patient well-being and quality of care. These preliminary findings warrant confirmation in a larger cohort. References: 1. Influencia del ejercicio físico sobre los síntomas de la radioterapia en pacientes con cáncer de mama: revisión sistemática. P. Collado Chazarraa, ∗ y M. Santiná Vila b2. Tejada-Medina, V.; Franco, G.; Ventaja- Cruz, J. (2020). Efectos de un programa de intervención de actividad física en pacientes oncológicos: una revisión sistemática. Journal of Sport and Health Research. 12(1):126-139.3. S, C. K. et al. Structured Exercise after Adjuvant Chemotherapy for Colon Cancer. New England Journal of Medicine 0, (2025) Keywords: physical exercise, quality of life,
Routine use of ePROMs may help identify at-risk patients early and enable targeted supportive interventions to maintain treatment continuity References: 1. The Royal College of Radiologists (January 2019), The timely delivery of radical radiotherapy: guidelines for the management of unscheduled treatment interruptions Fourth edition</i>. Available at: Timely delivery of radical radiotherapy: guidelines for the management of unscheduled treatment interruptions, Fourth edition | The Royal College of Radiologists [Accessed 14/07/2025]2. Hemingway H, Croft P, Perel P, Hayden J A, Abrams K, Timmis A et al. Prognosis research strategy (PROGRESS) 1: A framework for researching clinical outcomes BMJ 2013; 346 :e5595 doi:10.1136/bmj.e5595 (February 2013). Available at: https://www.bmj.com/content/bmj/346/bmj.e5595. full.pdf [Accessed 09/11/2025] Keywords: interruptions, ePROMs Enhanced Quality of Life in Radiotherapy Patients Following a 3-Month Structured Exercise Program: A Prospective Survey Analysis Victoria Vera Barragán 1 , Pablo Arrufat Porras 2 , Jose Antonio Portillo Valencia 2 , Carmen Corral Fernandez 1 , Alejandro Luis Ortiz Barrón 2 , Oscar González Expósito 2 , Juan Quirós Rivero 1 , Maria Dolores Apolo Arenas 3,4 1 Radiation Oncology, Hospital Universitario de Badajoz, Badajoz, Spain. 2 Physical Activity and Sport Sciences, Entrena tu Salud. Physical Exercise Center, Badajoz, Spain. 3 Medical-Surgical Therapy, University of Extremadura, Badajoz, Spain. 4 Research Group FhysioH, University of Extremadura, Badajoz, Spain Purpose/Objective: Radiotherapy, alongside hormonal and systemic therapies, can cause treatment-related side effects such as fatigue and dyspnea, temporarily impairing patient´s quality of life (QoL). Exercise has emerged as a safe and effective non-pharmacological strategy to support patients during and after oncologic treatments, improving functional capacity and overall well-being.Despite increasing evidence, structured Digital Poster 3463 exercise programs remain uncommon within radiotherapy departments.This study presents preliminary results from a prospective analysis evaluating the impact of a supervised three-month exercise program on QoL, assessed with the EORTC QLQ-C30 questionnaire in patients at different stages
of cancer treatment. Material/Methods:
A prospective study was conducted in 11 patients: seven participated in a supervised combined strength
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