S350
Clinical - Breast
ESTRO 2026
Conclusion: As per our statistical analysis, there is a numerical dosimetric benefit observed with DIBH in terms of several OARs, such as heart, left breast, left ventricle, right atrium and ventricle, IVC and aorta. However, these values could not be translated into statistical significance. Overall, we could not establish any added benefit of performing DIBH instead of the conventional free breathing technique of radiation delivery in terms of OAR doses, which subsequently translate to long term toxicities. However, further evaluation in a larger cohort is required to substantiate the dosimetric benefits of DIBH in cases of right sided breast cancer; along with correlation of these values with long-term clinical outcomes in these patients. References: 1. Pandeli C, Smyth LML, David S, See AW. Dose reduction to organs at risk with deep-inspiration breath-hold during right breast radiotherapy: a treatment planning study. Radiat Oncol. 2019;14(1):223. doi:10.1186/s13014-019-1430-x2. Mader T, Pace R, Boucas da Silva RT, Morais AC, Linero-Camacho LP, Meier N, et al. Deep inspirational breath hold (DIBH) for right breast irradiation:
For statistical analysis, paired t-test was used for each dosimetric parameter to evaluate the differences between both the plans (Table-2)
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