S470
Clinical - Gynaecological
ESTRO 2026
Purpose/Objective: Uterine cancers are treated with a multimodal approach including surgery, chemotherapy, external beam radiotherapy, and brachytherapy. Despite therapeutic advances, these cancers remain a threat, impacting patients' femininity and intimacy, and leading to challenges within the conjugal relationship.Given that this aspect has been underrepresented in previous studies, our study aimsto describe the impact of uterine cancers and their treatments on conjugal life. Material/Methods: This was a descriptive cross-sectional study conducted at the the Salah Azaïez Institute. It included patients followed for uterine cancers. Data were collected via a 40-minute interview using a questionnaire focusing on conjugal life. Results: A total of 100 patients treated between January and June 2019 were included in this study.The average age was 53.92 years (28- 74). Most patients (54%) had endometrial cancer, while 46% had cervical cancers. Treatment modalities included surgery (73%), chemotherapy (35%), external beam radiotherapy (65%), and brachytherapy (93%).All patients were married at the time of diagnosis.Prior to the illness, 81% of couples reported a relationship quality ranging from "happy" to "very happy." After treatment, the quality of the relationship evolved: 53% remained stable, 16% improved, and 31% deteriorated. The relationship quality remained "happy" to "very happy" for 72% of patients. Deterioration contributed to 6 cases of divorce (6%), all occurring in patients with cervical cancer.Among divorced cases, separation was initiated by the spouse in 66.7% of cases and by the patient in 33.3% of them.Spousal support was reported by 86% of women, characterized by emotional validation and caregiving. Conversely, 14% reported negative reactions, including emotional distance, verbal abuse, and devaluation. A major communication deficit was noted, with 48% of patients reporting
communication problems with their spouse. Misconceptions were prevalent: 16% of patients and 18% of spouses considered these cancers to be sexually transmissible or contagious, and 40% of women were unaware of their husband's opinion on this contagiousness. Conclusion: Uterine cancer and its treatment can have a major detrimental effect on the couple’s relationship and body image. Despite a high rate of spousal support, a significant minority of women face negative reactions, highlighting the need for better psychosocial support. Keywords: Uterine cancer, Conjugal life Digital Poster 3414 Using Patient Reported Outcomes (PRO) for organ dose guidance: weekly gastrointestinal symptom evolution during radiotherapy for cervix cancer. Enar Recalde Vizcay 1,2 , Marc Riera-Pons 3 , Savannah Pie Padro 4 , Marcelino Hermida Lopez 4 , Emmanuel Gimenez Garcia 5 , Gemma Galan Martinez 6 , Xavier Maldonado Pijoan 1,2 , Soraya Mico Milla 1,2 1 Radiation Oncology, Vall d'Hebron University Hospital, Barcelona, Spain. 2 Radiation Oncology Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. 3 Physics and Radiation ProtectionDepatment, Vall d'Hebron University Hospital, Barcelona, Spain. 4 Physics and Radiation Protection Depatment, Vall d'Hebron University Hospital, Barcelona, Spain. 5 Decision Support Unit, Vall d'Hebron University Hospital, Barcelona, Spain. 6 Scientific Project Manager, Vall d'Hebron Institute of Research (VHIR), Barcelina, Spain
Purpose/Objective: Clinician-reported (CR) outcomes are
routinely correlated with dosimetric data, but integrating patient's perspectives is essential for treatment optimization. EMBRACE-II1
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