S491
Clinical - Gynaecological
ESTRO 2026
n=888), (3) Surgery (n=2108). Prevalence of sexual inactivity (‘Not at all’) was 29% in the reference cohort, 31% in the surgery cohort, and 53% in the radiotherapy cohort. Prevalence of dyspareunia (‘A little’, ‘Quite a bit’, ‘Very much’) was 23% in the reference cohort, 39% in the surgery cohort, and 54% in the radiotherapy cohort. Sexual inactivity was directly associated with age, treatment modality, and social functioning. Social functioning was associated with body image, cognitive and role functioning, global QoL, and financial difficulties, all of which associated strongly with fatigue. Dyspareunia was linked to vaginal functioning and soreness. Notably, the strong associations observed in the cancer cohort between fatigue and functional outcomes/QoL were absent in the reference cohort.
Figure 2. Bayesian Network Models for Dyspareunia: A) Reference Cohort, B) Cancer Cohort. Conclusion: Sexual inactivity and dyspareunia were more common in cervical cancer patients, particularly in those treated with radio(chemo)therapy. Differences in explanatory factors between cancer and healthy cohorts highlight the need for cancer- specific approaches to sexual rehabilitation. Keywords: Cervical Cancer, Sexual Outcomes, Machine Learning Treatment and outcomes of primary vaginal cancer. A single institution experience. Camelia Frimodig 1 , Erik lundin 1 , Linnea Karlsson 2 , Ulf Granlund 2 , Bengt Johansson 1 , Ruth Sanchez Hermansson 1 1 Department of oncology, Örebro University Hospital, Örebro, Sweden. 2 Department of radiation oncology, Örebro University Hospital, Örebro, Sweden Digital Poster 4906
Figure 1. Bayesian Network Models for Sexual Activity: A) Reference Cohort, B) Cancer Cohort.
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