14
HERRERA ET AL .
TABLE 4
(Continued)
Reference
Systematic review title
PICOS question (as written in the original article)
(c)
#1. In patients with peri-implantitis, what is the efficacy of non-surgical sub-marginal peri- implant instrumentation with mechanical/physical decontamination methods (e.g., air- polishing, sonic/ultrasonic devices, lasers) alone or combinations thereof, compared to non-surgical sub- marginal instrumentation with placebo decontamination (non-aiming at mechanical/physical decontamination, e.g., scalers to remove hard deposits with adjunctive saline irrigation), in terms of change in peri- implant PD and/or change in BOP, in parallel-arm and split-mouth RCTs with ≥ 10 recruited/randomized subjects per treatment arm, in controlled clinical trials and prospective cohort studies with ≥ 30 recruited subjects with ≥ 6 months duration? #2. In patients with peri-implantitis, what is the efficacy of non-surgical sub-marginal peri-implant instrumentation with mechanical/physical decontamination methods (e.g., air- polishing, sonic/ultrasonic devices, lasers) alone or combinations thereof and additional measures/ interventions (e.g., irrigation with antiseptics), compared to non-surgical sub-marginal instrumentation with placebo decontamination (non-aiming at mechanical/physical decontamination, e.g., scalers to remove hard deposits with adjunctive saline irrigation) and additional measures/ interventions (e.g., irrigation with antiseptics), in terms of change in peri- implant PD and/or change in BOP, in parallel- arm and split-mouth RCTs with ≥ 10 recruited/randomized subjects per treatment arm, in controlled clinical trials and prospective cohort studies with ≥ 30 recruited subjects with ≥ 6 months duration? #3. In patients with peri-implantitis, what is the efficacy of non-surgical sub-marginal instrumentation with placebo decontamination (non-aiming at mechanical/physical decontamination, e.g., scalers to remove hard deposits with adjunctive saline irrigation) compared to no treatment or supramarginal mechanical cleaning in terms of change in peri-implant probing depth (PD) and/or change in bleeding on probing (BOP), in parallel-arm and split-mouth RCTs with ≥ 10 recruited/randomized subjects per treatment arm, in controlled clinical trials and prospective cohort studies with ≥ 30 recruited subjects with ≥ 6 months duration? In adult patients with peri-implantitis (P), what is the efficacy of sub- marginal instrumentation combined with chemical surface decontamination (I) in comparison with sub- marginal instrumentation with or without placebo (C), in terms of changes in PDs and/or BOP (O), as reported in RCTs, non-randomized controlled clinical trials (CCTs) or prospective cohort studies, with a minimum of 6-month ‘ follow-up ’ (S)? In patients diagnosed with peri-implantitis (population), which is the efficacy of patient-performed or administered adjunctive measures to non-surgical therapy (intervention) as compared to no adjunct (comparison), in terms of PD and/or BOP reductions (primary outcomes), reported in RCTs or CCTs with at least 6 months of follow-up (study design)? #1. In patients requiring treatment of peri-implantitis (P), what is the effect of surgical therapy including access flap or pocket elimination procedures (I), when compared to non-surgical therapy (C), in terms of reduction of PD and/or of BOP (O), as observed in randomized controlled trials with a follow-up of ≥ 6 months and a sample size of ≥ 10 patients per arm (S)? #2. In patients requiring treatment of peri-implantitis, what are the long- term outcomes of surgical access flap or pocket elimination procedures based on prospective studies (interventional or observational) with a sampleof ≥ 20 patients and a follow-up of ≥ 12months?
Cosgarea et al. (2023)
Efficacy of mechanical/physical approaches for implant surface decontamination in non- surgical sub-marginal instrumentation of peri- implantitis. A systematic review.
de Waal et al. (2023)
Efficacy of chemical approaches for implant surface decontamination in conjunction with sub-marginal instrumentation, in the non- surgical treatment of peri-implantitis. A systematic review and meta-analysis.
Liñares et al. (2023)
Efficacy of adjunctive measures in the non- surgical treatment of peri-implantitis. A systematic review.
(d)
Karlsson et al. (2023)
Efficacy of access flap and pocket elimination procedures in the management of peri- implantitis — a systematic review and meta- analysis
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