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Appendix 4
technology
Study Hunter: APAP Effectiveness in prisma Examination of the Effectiveness of FOT-based auto-CPAP Therapy Device in the Treatment of Patients with Obstructive Sleep Apnea S.D. Herkenrath, M. Treml, N. Anduleit, K. Pietruska, M. Schwaibold, W.J. Randerath, Scientific Institute for Pneumology at University of Cologne. Poster (German, English, French), ERS 2018 Background: The Forced Oscillation Technique (FOT) is proven to be a sound method for apnea classification in APAP devices. This clinical study examines - The effectiveness of pressure regulation and - analyses associations between applied therapy pressure and mask leakage. Overall Message: The algorithm in prisma20A does not need to fear the comparison with competition! The algorithm is effective. The results apply to all APAP modes in prisma devices as well. Main results: - Obstructions were treated effectively. - Even at higher pressures there was no risk that APAP pressure is “overshooting”. - Even though most patients wore a nasal mask there was hardly any mouth leakage measured. Further Conclusion: - Our devices do not provoke or induce central events. - It was proven that APAP pressure was only moderately increased to treat events effectively (Löwenstein philosophy). Method:
- 34 OSAS patients, baseline diagnosis of AHI >15 - Open pressure thresholds from 4hPa – 20hPa - 1 diagnosis night, 1 therapy night - Standard APAP regulation Further Comment: Further publications are in progress. You will be informed.
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