Research Report 2019_20

HudsonAlpha Adjunct Faculty

Jeremy Day, PhD is an assistant professor in the Department of Neurobiology at The University of Alabama at Birmingham. Day received his PhD from the University of North Carolina at Chapel Hill in 2009 and completed a postdoctoral fellowship at UAB in the Department of Neurobiology. He joined the neurobiology faculty at UAB in 2014, where his lab investigates the neurobiology of reward-related memory systems in the brain and the role of these circuits in drug addiction. His research integrates molecular, physiological, behavioral, genetic and epigenetic tools to understand how experience alters the brain and how those changes drive future behaviors.

Jeremy Day, PhD

Anindya Dutta, PhD, MBBS is chair of the Department of Genetics at the University of Alabama at Birmingham School of Medicine. Dutta joined UAB School of Medicine from the University of Virginia School of Medicine, where he is the chair of the Department of Biochemistry and Molecular Genetics. He was recognized there with the Distinguished Scientist Award for his work on genome instability and noncoding RNAs in cancer. The Department of Genetics has a longstanding reputation for delivering outstanding care for patients and families through integrated clinical and laboratory services.

Anindya Dutta, PhD

Anna Hurst, MD, MS is an assistant professor of medical genetics in the Department of Genetics at The University of Alabama at Birmingham. She trained as a genetic counselor at the University of South Car- olina School of Medicine (Columbia) and then completed her medical degree at the Medical University of South Carolina (Charleston). She is a board-certified pediatrician who completed pediatrics residency at Wake Forest Baptist Health (Winston-Salem, NC) and a medical genetics residency at UAB. Hurst is a clinician for the UAB Undiagnosed Disease Program, skeletal dysplasia clinic, and general genetics, and she provides genetic inpatient hospital consultations for patients at UAB and Children’s of Alabama. Her research focuses on expanding the availability of genomic sequencing for children with complex health- care needs and incorporating phenotypic information into the interpretation of genomic data. Bruce Korf, MD, PhD is a professor in the Department of Genetics at the University of Alabama at Birmingham, and the chief genomics officer of UAB Medicine. He also is co-director of the UAB- HudsonAlpha Center for Genomic Medicine. Korf is past president of the Association of Professors of Human and Medical Genetics and of the American College of Medical Genetics and Genomics and cur- rently is president of the ACMG Foundation for Genetic and Genomic Medicine. He completed his un- dergraduate studies and MD at Cornell University and received his PhD in genetics and cell biology from Rockefeller University. He then did training in pediatrics, child neurology and genetics at Children’s Hospital, Boston, and is board certified in all three areas, as well as clinical cytogenetics and clinical molecular genetics. His research focus is the genetics and treatment of neurofibromatosis type 1, and he also has a major interest in genetics and genomics education and the integration of genetics into medical practice. Eric Mendenhall, PhD is an associate professor at The University of Alabama in Huntsville. His re- search is directed at defining the function of the regulatory or non-coding regions of the genome. These regions control how genes are turned on or off in the appropriate cells of our bodies. The lab focuses on developing methods to define what determines a functional regulatory region, investigating how the DNA sequence establishes these regions and understanding how variation in human DNA can alter this regulation to produce human traits and human genetic diseases. This requires the lab to develop and use specific synthetic biology tools, including customizable DNA binding proteins (TALEs and Crispr/Cas), synthetic DNA libraries and next-generation sequencing to assign biological functions to non-coding regions of the genome.

Anna Hurst, MD, MS

Bruce Korf, MD, PhD

Eric Mendenhall, PhD

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