Sciatica is a symptom of pain typically referred into the lower extremity as result of injury to the sciatic nerve. This nerve is comprised of spinal nerves derived from the lumbosacral spine from L4-S2. The most common causes of sciatica are disc conditions such as herniations, disc degeneration, spinal stenosis, and vertebral slippage (spondylolisthesis). These problems are associated with compression on spinal nerves and localized inflammation. An uncommon form of sciatica is caused by a buttocks muscle which when in spasm can compress a portion of the sciatic nerve (Piriformis syndrome).
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