Riley Children's Health Annual Report – October 2026

NOTABLE PUBLICATIONS

RILEY HEART CENTER

With 155 years of combined surgical experience, the cardiovascular surgeons at Riley Children’s Health treat and manage the full spectrum of heart defects—from the most common to the most rare and complex. Practicing at the highest level of board certification, our heart surgeons offer a degree of expertise found only in the most advanced pediatric hospitals. CARDIOTHORACIC SURGERY

30-day Survival: 2023 – 2025 Index

World Journal for Pediatric and Congenital Heart Surgery: May 2026 Pulmonary autograft mitral valve replacement (Ross II procedure): More than two decades of follow-up from a single center in the United States World Journal for Pediatric and Congenital Heart Surgery: November 2025 Outcomes and predictors of failure of systemic-to-pulmonary shunts: Experience of a single institution over 14 years World Journal for Pediatric and Congenital Heart Surgery: July 2025 Right atrial rhabdomyosarcoma; 35-year disease-free survival following radical resection with right internal thoracic artery bypass The Journal of Innovations in Cardiac Rhythm Management: July 2025 Preserved subcutaneous implantable cardioverter-defibrillator function following septal myectomy and coronary artery unroofing in a pediatric patient with severe hypertrophic cardiomyopathy

All

operations †††

operations

99%

96%

2023

98%

96%

2024

99%

98%

2025

Premier programs

TOP DISTINCTIONS

††† The first cardiac operation of a hospitalization

■ Cardiovascular Genetics Program ■ Aortopathy Program ■ Adult Congenital Heart Disease Program ■ Cardiac Rehabilitation Program ■ Single Ventricle Home Monitoring Program ■ Ventricular Assist Device Home Monitoring Program ■ Fontan Program

■ Exceptional heart transplant outcomes – One-year patient survival remains at 100%; exceeds the national average. * – Three-year patient survival is 90%; exceeds the national average. * – Our surgeons are performing more transplants for patients with neonatal Marfan’s syndrome. ■ Only pediatric and adult congenital heart transplant program in Indiana; program accredited by the Adult Congenital Heart Association ■ Seven decades of experience with right ventricular outflow tract reconstruction ■ Riley Heart Center meets the criteria of a “Comprehensive Care Center,” a top-tier designation based on updated pediatric heart surgery national standards **

Postoperative Overall Complications The Society of Thoracic Surgeons (STS) Participant Dashboard for period July 1, 2021 – June 30, 2025

No complications identified Riley Children’s 59.09% STS overall 53.52%

One or more complications identified Riley Children’s 40.91% STS overall 45.94%

Our surgeons are able to minimize cross-clamp time and in nearly all categories achieve less time on bypass than the national average.

Median CPB and Cross Clamp Time for Select Procedures (in minutes) ††

Advanced therapies and procedures ■ Dedicated simulation lab that includes training on ventricular assist devices ■ Pioneer in using the Berlin Heart to manage pediatric heart failure; only Indiana program to offer it Operative and Adjusted Operative Mortality ***

CPB TIME

RILEY CHILDREN’S

STS

49.5

47 76

ASD

64 97

VSD

109 140

Coarctation

106

AV Canal, Complete

EXPECTED MORTALITY RILEY CHILDREN’S

OBSERVED MORTALITY RILEY CHILDREN’S

NEONATES/INFANTS/ CHILDREN/ADULTS

STS OVERALL

64

104.5

Aortic Valvuloplasty

153 149

162 165

TGA with IVS, Switch

All STAT Mortality Categories STAT Category 1 (Least risk)

3.07%

3.43%

2.65%

Norwood

CROSS-CLAMP TIME

RILEY CHILDREN’S

STS

0.61%

0.65%

0.62%

26 35 37 74

25 50 43

ASD

DIVISION CHIEF Mark W. Turrentine, MD John W. Brown Professor of Cardiothoracic Surgery, IU School of Medicine Organ Procurement & Transplantation Network primary surgeon > Connect with Dr. Turrentine on Doximity.

1.80%

1.26%

1.95%

STAT Category 2

VSD

Coarctation

3.99%

5.00%

3.25%

STAT Category 3

107

AV Canal, Complete

Riley Children’s is ranked among the top programs in the nation for complex pediatric heart surgery volume. Source: U.S. News & World Report

8.51%

6.78%

7.32%

STAT Category 4

35.5

72

Aortic Valvuloplasty

STAT Category 5 (Most risk)

17.91%

33.90%

15.44%

73 52

101

TGA with IVS, Switch

3 board certified physicians

See full team member list >

71

Norwood

Note: Per STS, observed mortality is as expected based on institution’s case mix.

One-year operative mortality rate at Riley Children’s is lower than STS (1.59% vs. 2.39%). †

†† Source: Society of Thoracic Surgeons (STS) Harvest Report, published December 2025 for period ending June 30, 2025

* Source: Scientific Registry of Transplant Recipients (SRTR) Tables C19D and C20D, released Jan. 6, 2026, for period July 1, 2022 -- Dec. 31, 2024 (one year) and Jan. 1, 2020 – March 12, 2020, and June 13, 2020 – June 30, 2022 (three year) ** Recommendations for centers performing pediatric heart surgery in the United States *** Source: Society of Thoracic Surgeons (STS) Table 16, Harvest Report, published December 2025 for period ending June 30, 2025 † Source: Society of Thoracic Surgeons (STS) Table 1, Harvest Report, published December 2025 for period ending June 30, 2025

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