RESEARCH HIGHLIGHTS
CARDIAC CRITICAL CARE MEDICINE RILEY HEART CENTER
■ Founding member and coordinating center: Collaborative Research in Pediatric Cardiac Intensive Care (CoRe-PCIC) network; multiple U.S. sites participating in several ongoing research projects ■ Riley Children’s is a member of the Pediatric Cardiac Critical Care Consortium (PC4), which uses registry data from more than 60 congenital heart programs to evaluate best practices and drive improvements.
The expert cardiac critical care physicians at Riley Children’s Health provide specialized care for critically ill newborns, infants, children and adolescents with congenital and acquired heart disease. Our high-acuity, high-volume CVICU includes 23 beds for CVICU patients and an eight-bed specialized neonatal ICU.
The cardiac critical care team is actively enrolling in prospective observational cohort studies and clinical trials focused on multiorgan dysfunction (including acute respiratory
Advanced technologies and procedures
TOP DISTINCTIONS
■ Ventricular assist devices (VAD) – We offer a wide range of circulatory support devices to support patients in bridge-to-transplant or bridge-to-recovery circumstances. ■ Continuous renal replacement therapy (CRRT) – In addition to a multidisciplinary CRRT program, Riley Children’s offers aquapheresis to remove excess fluid accumulation in critically ill neonates and children. ■ Etiometry software – All CVICU rooms are equipped with this FDA-approved software visualization application to collect, store and present ICU data in near real time.
distress syndrome, sepsis, renal failure and ECMO support).
■ Only program in Indiana to offer pediatric heart transplantation and mechanical circulatory support capability ■ Indiana’s only pediatric hospital with a formal extracorporeal cardiopulmonary resuscitation (ECPR) program ■ Riley Heart Center meets the criteria of a “Comprehensive Care Center,” a top-tier designation based on updated pediatric heart surgery national standards *
Postoperative Overall Complication – Unadjusted Riley Children’s 28% All PC4 ** facilities 34.2% Postoperative Severity – Adjusted CVICU Length of Stay Riley Children’s 12.4 days All PC4 ** facilities 10.9 days
NOTABLE PUBLICATIONS
Respiratory Care: March 2025 Ventilator liberation practices in pediatric cardiac critical care World Journal for Pediatric and Congenital Heart Surgery: January 2025 Prospective evaluation of extubation failure in neonates and infants after cardiac surgery Cardiology in the Young: December 2025 Serum carnitine profile changes after open heart surgery in children with CHDs Resuscitation: October 2025 Pediatric life support: 2025 International Liaison Committee on Resuscitation consensus on science with treatment recommendations Resuscitation: November 2025 Outcomes in pediatric ECPR for in-hospital cardiac arrest: An ELSO registry analysis World Journal for Pediatric and Congenital Heart Surgery: July 2025 Liposomal bupivacaine versus plain bupivacaine for pain control following congenital cardiac surgery
High-volume pediatric ECMO center
Major Complications – Unadjusted Riley Children’s 18.1% All PC4 ** facilities 23%
■ Riley Children’s is designated a Platinum Level Center of Excellence by the Extracorporeal Life Support Organization. ■ Over the past five years, our overall survival rate for cardiac ECMO patients is higher than 60% (above the national average). ■ To date, Riley Children’s has treated more than 1,300 patients with ECMO.
The Society of Pediatric Sedation has designated Riley Children’s a Center of Excellence in Procedural Sedation.
ALTERNATIVE COMPLICATIONS
CASES OUT OF RILEY CHILDREN’S ALL PC4 ** FACILITIES
CLABSI per 1,000 line days (central line-associated bloodstream infection)
0.2 per 1,000
1 5,064
1.09 per 1,000
Risk-adjusted CVICU Surgical Mortality ***
Risk-adjusted CVICU Medical Mortality ***
CAUTI per 1,000 catheter days (catheter-associated urinary tract infection)
1.58 per 1,000
2 1,268
0.81 per 1,000
DIRECTOR Riad Lutfi, MD Professor of Clinical Pediatrics, IU School of Medicine > Connect with Dr. Lutfi on Doximity.
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3.98%
3.32%
Unplanned extubation per 100 ventilator days
0.49 per 100
14 2,849
0.23 per 100
2.08%
SSI per 100 surgical procedures (surgical site infection)
1.08%
0 per 100
0 755
0.85 per 100
10 board certified physicians (plus multiple board certified neonatologists and physicians in other specialties)
See full team member list >
Data reflects July 1, 2024 – June 30, 2025, outcomes.
Riley Children’s All PC4 ** facilities
Riley Children’s All PC4 ** facilities
** Pediatric Cardiac Critical Care Consortium | Data reflects July 1, 2024 – June 30, 2025 , outcomes. *** Risk adjustment is a methodological approach incorporating unique patient characteristics that impact patient outcomes and are unrelated to the quality of care delivered by the care team or hospital.
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* Recommendations for centers performing pediatric heart surgery in the United States
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